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Found 26 clinical trials
Subthreshold Laser Treatment in Intermediate Age-related Macular Degeneration With Nascent Geographic Atrophy Study (LIANA)

progression in eyes with intermediate age-related macular degeneration (AMD) and nascent geographic atrophy by functional and anatomical outcomes. The study population will be individuals with high

retinal pigment
drusen
geographic atrophy
spectral domain optical coherence tomography
corrected visual acuity
  • 0 views
  • 26 Mar, 2022
  • 1 location
Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophy (LADIGAGA)

The primary objectives of the study are to assess the safety, tolerability and evidence of activity of 12 months oral treatment with TEFIDERA® in subjects with Geographic Atrophy associated with

atrophy
retinal pigment
geographic atrophy
  • 0 views
  • 24 Mar, 2022
Metabolomics: A Novel Tool for Investigating the Pathogenesis of Age-related Macular Degeneration (AMDMetab)

potentially blinding late forms (choroidal neovascularization or geographic atrophy). Individuals vary in their rate of progression, with some remaining stable for years. The reasons behind this variability

atrophy
neovascularization
Accepts healthy volunteers
geographic atrophy
  • 0 views
  • 21 Jul, 2022
  • 1 location
A Study to Evaluate the Safety and Efficacy of RQC for AMD

To evaluate the safety and efficacy of resveratrol, quercetin, and curcumin in combination (RQC) over 2 years in patients with age-related macular degeneration (AMD).

atrophy
drusen
geographic atrophy
  • 0 views
  • 06 Oct, 2021
A Study of Danicopan in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

This is a dose finding study designed to evaluate the efficacy, safety, and pharmacokinetics of danicopan in participants with GA secondary to AMD. The study consists of a Screening Period of up to 6 weeks, a 104-week masked Treatment Period, followed by a 30-day Follow-up after the last dose. This …

atrophy
geographic atrophy
  • 1 views
  • 25 Jul, 2022
  • 34 locations
GOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)

The purpose of the study is to evaluate the effect of IONIS-FB-LRx on the rate of change of the area of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) measured by

pneumoniae
macular degeneration
corrected visual acuity
mydriasis
fundus autofluorescence
  • 1370 views
  • 26 Apr, 2022
  • 85 locations
Restoration of Central Vision With the PRIMA System in Patients With Atrophic AMD (PRIMAvera)

The objective of this study is to evaluate the efficacy and safety of the PRIMA System in patients with atrophic AMD. Eligible subjects will be implanted with the PRIMA Implant. The subjects will be assessed with various visual function and functional vision tests at defined timepoints throughout the clinical investigation …

atrophy
vision test
corrected visual acuity
geographic atrophy
  • 0 views
  • 21 Jul, 2022
  • 17 locations
EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

The purpose of this clinical study is to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age

  • 82 views
  • 10 Dec, 2021
  • 30 locations
HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

The purpose of this clinical study is to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age

  • 73 views
  • 10 Aug, 2022
  • 63 locations
ONL1204 Ophthalmic Solution in Patients With Geographic Atrophy Associated With Age-related Macular Degeneration

The purpose of this study is to evaluate the safety and tolerability of intravitreal injection of ONL1204 Ophthalmic Solution in patients with geographic atrophy associated with AMD

fundus autofluorescence imaging
neovascularization
geographic atrophy
atrophy
detachment
  • 5 views
  • 08 Aug, 2021
  • 1 location