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Found 27 clinical trials
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A Phase 3 Multicenter, Randomized, Double Masked, Sham- Controlled Clinical Trial to Assess the Safety and Efficacy of Intravitreal Administration of Zimura (Complement C5 Inhibitor) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

The objectives of this study are to evaluate the safety and efficacy of Zimura intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD

  • 0 views
  • 24 Jun, 2021
  • 1 location
None
Alpha MSH in Ocular Disease

studying the levels of alpha MSH in your eye we may better understand its role in advanced dry macular degeneration. By studying the levels of this molecule we hope to better understand if it may be a good

  • 36 views
  • 27 Jan, 2021
  • 1 location
None
Metabolomics: A Novel Tool for Investigating the Pathogenesis of Age-related Macular Degeneration

potentially blinding late forms (choroidal neovascularization or geographic atrophy). Individuals vary in their rate of progression, with some remaining stable for years. The reasons behind this variability

neovascularization
geographic atrophy
atrophy
  • 0 views
  • 08 Jul, 2021
  • 1 location
None
TTT Versus PDT for Treatment of Choroidal Neovascularization in Age-Related Macular Degeneration

( AMD). AMD is a disease affecting the macula, the central area of the retina.There are two main types of AMD. Geographic atrophy ( dry) AMD and neovascular ( wet) AMD. In neovascular AMD, sub

neovascularization
angiography
visual loss
macular degeneration
photodynamic therapy
  • 19 views
  • 07 Nov, 2020
  • 1 location
None
A Study to Evaluate the Safety and Efficacy of RQC for AMD

To evaluate the safety and efficacy of resveratrol, quercetin, and curcumin in combination (RQC) over 2 years in patients with age-related macular degeneration (AMD).

geographic atrophy
atrophy
drusen
  • 0 views
  • 06 Oct, 2021
None
GOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)

The purpose of the study is to evaluate the effect of IONIS-FB-LRx on the rate of change of the area of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) measured by

macular degeneration
atrophy
mydriasis
fundus autofluorescence
vaccination
  • 521 views
  • 13 Oct, 2021
  • 156 locations
None
EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

The purpose of this clinical study is to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age

  • 57 views
  • 10 Oct, 2021
  • 24 locations
None
HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

The purpose of this clinical study is to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age

  • 0 views
  • 10 Oct, 2021
  • 42 locations
None
Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD

geographic atrophy in non-diabetic patients with Age-related Macular Degeneration (AMD).

drusen
macular degeneration
atrophy
mydriasis
geographic atrophy
  • 370 views
  • 11 May, 2021
  • 13 locations
None
ONL1204 Ophthalmic Solution in Patients With Geographic Atrophy Associated With Age-related Macular Degeneration

The purpose of this study is to evaluate the safety and tolerability of intravitreal injection of ONL1204 Ophthalmic Solution in patients with geographic atrophy associated with AMD

neovascularization
detachment
geographic atrophy
atrophy
fundus autofluorescence imaging
  • 5 views
  • 08 Aug, 2021
  • 1 location