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Found 317 clinical trials
Methods for Increasing Genetic Testing Uptake in Michigan (MiGHT)

of a participant obtaining guideline-concordant genetic testing. Eligible participants will be randomized (assigned) to one of the following interventions: 1) Virtual genetics navigator, a mobile

breast cancer
triple negative breast cancer
cancer
cancer of the ovary
ovarian cancer
  • 0 views
  • 16 Jun, 2022
  • 1 location
Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

This randomized clinical trial studies how well online genetics educational video with or without pre- and/or post-telephone genetics counseling works in assessing cancer-risk distress in patients with triple negative breast cancer. Online genetic education and telephone genetic counseling may help the doctors learn the stress a person feels about their …

estrogen receptor
epidermal growth factor receptor
human epidermal growth factor
progesterone
progesterone receptor
  • 24 views
  • 01 Jul, 2022
  • 2 locations
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States (GUARDD-US)

The primary aim is to determine the effect of participant and provider knowledge of a positive APOL1 status and accompanying guideline based clinical decision support (CDS) on blood pressure management on change in systolic blood pressure (SBP) from baseline to 3 months after randomization among the APOL1 positive participants. Secondary …

antihypertensive drugs
apolipoprotein l1
hemoglobin a1c
hypertension
diabetes
  • 0 views
  • 20 Apr, 2022
  • 9 locations
Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients

This study aims to determine if web-based eHealth delivery of pre-test and/or post-test counseling in cancer patients and/or those at risk for cancer can provide equal or improved cognitive and affective outcomes when compared to the standard of care delivery model.

breast cancer
genetic testing
Accepts healthy volunteers
advanced cancer
stage iv breast cancer
  • 0 views
  • 28 Oct, 2021
  • 1 location
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's

pembrolizumab
erlotinib
carcinoma
paclitaxel
crizotinib
  • 1154 views
  • 28 Jun, 2022
  • 1035 locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of

brain tumor
serum pregnancy test
binimetinib
antiretrovirals
pertuzumab
  • 6575 views
  • 27 Jun, 2022
  • 913 locations
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin

blood count
cytotoxic chemotherapy
blood transfusion
hematopoietic growth factors
myelosuppressive chemotherapy
  • 1032 views
  • 01 Jul, 2022
  • 106 locations
FaCT Trial (Facilitated Cascade Testing Trial)

The purpose of this study is to assess an intervention that incorporates engagement strategies with a medical team navigator, an educational video and accessible genetic testing services to

Accepts healthy volunteers
  • 0 views
  • 03 May, 2022
  • 3 locations
Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients

blastocyst transfer in preimplantation genetic testing (PGT) patients, with biopsy on day 5 of embryonic development. The advantage of performing the study in PGT patients is the exclusion of aneuploidy as a

progesterone
embryo transfer
  • 32 views
  • 09 Feb, 2022
  • 1 location
Identifying and Caring for Individuals With Inherited Cancer Syndrome

This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public

breast cancer
genetic testing
BRCA1
cancer
carcinoma
  • 21 views
  • 23 Mar, 2022
  • 2 locations