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Found 316 clinical trials
Pharmacogenetic Supported Prescribing in Kids

Implementation of pharmacogenetic testing for children and adolescents aged 7-17 who are starting or changing psychiatric medication.

  • 23 Mar, 2021
  • 1 location
Telephone Versus In-person Post-test Cancer Genetic Counseling

The purpose of the GEO-STAR randomized non-inferiority trial is to compare the outcome of post-test telephone cancer genetic counseling with standard in-person cancer genetic counseling. We hypothesize that telephone counseling is non-inferior by outcome if compared to standard in-person counseling.

  • 05 Aug, 2021
  • 1 location
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.

Accepts healthy volunteers
  • 17 Jun, 2022
  • 77 locations
Cascade Genetic Testing of Familial Hypercholesterolemia (CATCH)

with FH, cascade genetic testing in families is recommended by many cardiovascular prevention guidelines. However, the implementation of national genetic cascade screening is challenging, because legal

myocardial infarction
cardiovascular disease
genetic analysis
genetic disorder
  • 03 Jun, 2022
Preimplantation Genetic Testing in Women of Advanced Maternal Age

The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo

  • 07 Aug, 2021
  • 1 location
Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure

Assessing whether Preimplantation Genetic Testing for Aneuploidy (PGT-A) can increase the ongoing pregnancy rate per transferred embryo and can decrease the time to pregnancy and miscarriage

  • 16 Oct, 2021
  • 1 location
SBRT in Combination With Sintilimab and GM-CSF for the Treatment of Advanced NSCLC

The goal of this study is to design a means of providing research families, from diverse geographical locations, the chance to receive genetic testing after having been educated by video, and

  • 23 Jan, 2021
  • 1 location
Antidepressant Discontinuation in Treatment Resistant Depression

opportunity to undergo genetic testing for the serotonin gene transporter which has a short or long form. This is being done because it has been demonstrated that genetic testing improves outcome while

depressive symptoms
depressive disorder
  • 04 Jun, 2022
  • 1 location
Drug Combinations of Atovaquone-Proguanil (AP) With ACT

for malaria at the same time), as long as well tolerated, can provide cure in patients that harbor parasites not responsive to standard first-line medications. Human genetic testing will be done to

  • 08 Mar, 2021
  • 3 locations
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients

metabolic activity and also perform a genetic analysis. The genetic testing is specifically to analyze the following genotypes only: cytochrome P450 2D6 (CYP2D6) and cytochrome P450 3A4 (CYP3A4), which

  • 17 Jun, 2022
  • 1 location