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Found 57 clinical trials
Bipolar Genetics: A Collaborative Study

This study looks to identify genes that may affect a person's chances of developing bipolar disorder (BP) and related conditions.

bipolar disorder
Accepts healthy volunteers
neurological disorder
  • 13 Oct, 2022
  • 1 location
Multimodal Neuroimaging Genetic Biomarkers of Nicotine Addiction Severity

Background Smoking is a difficult habit to quit, and some people find it more difficult to quit than others do. Nicotine is the substance in cigarettes that makes smoking so addictive. Nicotine changes some patterns of brain activity, and smokers have differences in brain activity when compared to non-smokers. Some …

urine cotinine test
Accepts healthy volunteers
urine cotinine
drug use
  • 23 Oct, 2022
  • 1 location
DHS MIND Metabolomics

The study team will evaluate whether metabolomic signatures of neurocognitive decline trajectories are exacerbated by the presence of type 2 diabetes mellitus (T2D) and whether these signatures contribute in part, to ethnic disparities in cognitive decline between European Americans and African Americans with T2D.

diabetic ketoacidosis
diabetes mellitus
type 2 diabetes mellitus
  • 21 Mar, 2022
  • 1 location
Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Diseases

Selected patients suspected of having or with prior biopsy proof of malignant disease will be seen in the Urologic Oncology Branch, NCI. Blood samples may be collected at the time of the initial visit and at periodic intervals during the course of the disease. These samples will be stored in …

Accepts healthy volunteers
  • 24 Oct, 2022
  • 1 location
Predictors of Better Outcomes After Severe Acquired Brain Injuries

Severe Acquired Brain Injury is defined as a traumatic, post-anoxic, vascular or other brain damage that causes coma for at least 24 hours and leads to permanent disability with sensorial, motor, cognitive or compartmental impairment. In this context, an accurate characterization of individual patients' profile in terms of neuronal damage, …

  • 24 Jan, 2021
  • 1 location
Stockholm3 Validation Study in a Multi-Ethnic Cohort (SEPTA)

Introduction: Prostate cancer (PCa) is the most commonly detected cancer in men and is the second leading cause of cancer death. Differences in race and ethnicity have been shown to have differences in PCa incidence, detection, and outcomes. Current prostate cancer screening involves prostatic specific antigen (PSA) which is a …

  • 07 Oct, 2022
  • 7 locations
Women's Advanced Risk-assessment in Manitoba (WARM)

The main objective of this study is to test the ability of novel cardiovascular disease (CVD) prognostic tools to identify women at risk for future CVD. We plan to establish a cardiovascular health screening program at the St. Boniface Hospital and to test the efficacy of these tests for predicting …

cardiovascular disease
  • 25 Feb, 2022
  • 1 location
Follow-up of Covid-19 Long Term Sequelae

The protocol, in accordance with the objectives of ORCHESTRA project - Work Package 2, aims at investigating the characteristics and determinants of COVID-19 long-term sequelae. This goal will be reached through the harmonization of follow-up strategies across the participating cohorts to allow a standardized collection of data on COVID-19 long-term …

  • 22 Mar, 2022
  • 7 locations
Clinical and Genetic Markers of Bone Metabolism in Children Under One Year

genotypes by polymorphisms, analysis of the relationship of molecular genetic markers with indicators of bone metabolism.

  • 30 May, 2022
  • 1 location
Pharmacogenomics of Asparaginase Induced Hepatotoxicity

samples may help doctors find certain genetic markers that may predict whether participants will tolerate asparaginase, which is given as part of clinical care for acute lymphoblastic leukemia.

lymphoid leukemia
  • 05 Feb, 2022
  • 1 location