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Found 59 clinical trials
Efficacy and Cost-effectiveness of Internet-delivered CBT for Adolescents With Depression

Selected patients suspected of having or with prior biopsy proof of malignant disease will be seen in the Urologic Oncology Branch, NCI. Blood samples may be collected at the time of the initial visit and at periodic intervals during the course of the disease. These samples will be stored in …

  • 15 Oct, 2021
  • 1 location
Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients

In North America, the number of new cases of prostate cancer increases every year. Many efforts have been made to develop more efficient and safer curative treatments for high risk prostate cancer patients. This phase III clinical trial is designed to compare the safety of a standard pelvic external beam …

external beam radiation therapy
ct scan
hormone therapy
bone scan
androgen suppression
  • 27 Sep, 2021
  • 13 locations
Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders

At least 60% of Veterans with an alcohol use disorder will relapse within 6 months of treatment, irrespective of the type of treatment they receive. This indicates that currently available interventions for treating AUD in Veterans are not effective in helping them achieve long-term sobriety. Repetitive transcranial magnetic stimulation (rTMS) …

addiction treatment service
psychiatric disorder
psychotropic drugs
withdrawal symptom
  • 03 Mar, 2022
  • 1 location
Relationship Between Improvement in Insulin Secretion and Decrease in HbA1c in GLP-1 RA Therapy in T2DM Patients

GLP-1 receptor agonists (GLP-1 RA) is group of antidiabetic agents very effective in lowering the plasma glucose concentration in T2DM patients . Currently there are several agents approved for the treatment of T2DM which are classified into two groups: (1) short acting GLP-1 RA and include exenatide BID and lexisenatide, …

plasma glucose
sglt2 inhibitor
glucagon-like peptide-1
  • 25 Jan, 2021
  • 1 location
Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer

This research study is comparing two standard of care treatment options based on blood test results for participants who have metastatic colorectal cancer. The names of the potential treatments involved in this study are: Active surveillance FOLFIRI treatment Nivolumab treatment Encorafenib/Binimetinib/Cetuximab treatment

adjuvant therapy
folfiri regimen
folfox regimen
  • 25 Feb, 2022
Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study) (ABC-X)

This is a phase II, open label, randomised trial of ipilimumab and nivolumab with concurrent intracranial stereotactic radiotherapy versus ipilimumab and nivolumab alone in patients with asymptomatic, untreated melanoma brain metastases.

  • 04 Oct, 2022
  • 5 locations
Bicuspid Aortic Valve (BAV) Registry (BAV)

The purpose of this registry is to gather information on patients with bicuspid aortic valve disease.

Accepts healthy volunteers
  • 25 Mar, 2022
  • 1 location
Freder1k-Study - Testing Infants for Type 1 Diabetes Risk

The Freder1k-Study will identify infants who have a high genetic risk of type 1 diabetes.

  • 16 Feb, 2021
  • 2 locations
FDG an Myocardial Infarction: The PIAF Trial

In order to define distinct and reliable arterial 18Fluorodeoxyglucose (FDG) thresholds identifying patients at risk for cardiovascular events, patients with a history of myocardial infarction will be included in this international multicenter trial. Non-enhanced whole-body FDG PET/CT will be performed in all patients and the arterial FDG uptake in the …

  • 10 Dec, 2021
Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis

undergo subsequent curve progression requiring intervention. The investigators hypothesize that alterations in specific genetic markers will be correlated with the progression of AIS curves over

  • 04 Oct, 2022
  • 1 location