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Found 29 clinical trials
Featured trial
Fox Insight - Online Parkinson's Health and Genetic Study

through Indiana University to help you understand your genetic test results.  Through this opportunity researchers can better understand Parkinson’s and potentially speed scientific breakthroughs.

Online studies
  • 10 Dec, 2021
  • 1 location
  • Online study
Featured trial
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Efficacy, Safety and Biomarker Effects of ALZ-801 in Subjects with Early Alzheimer’s Disease and APOE4/4 Genotype

This study is designed to evaluate the safety and efficacy of oral ALZ-801 in the treatment of early Alzheimer’s Disease (AD) with APOE4/4 genotype.

Accepts healthy volunteers
mild dementia
alzheimer's disease
cognitive assessment
  • 25 Jul, 2022
  • 1 location
Genetic Testing for Common Disorders: Learning from the Experiences of Individuals who were Tested to Determine their Genetic Risk for Alzheimer’s Disease

This study is looking for people who have the APOE-e4 gene, which is associated with a higher risk for developing Alzheimer’s disease. The study is interested in learning about participants’ experiences.IMPORTANT: This communication is meant only to make you aware of an opportunity to participate in a research study. The …

Online studies
Accepts healthy volunteers
  • 03 Mar, 2022
  • 1 location
  • Online study
OPTimizing Treatment Focused Genetic Testing IN Cancer (OPT-IN)

This two-part randomized controlled trial aims to evaluate the impact of pre-test video education as compared to pre-test Chatbot education.

  • 02 May, 2022
  • 1 location
Identifying and Caring for Individuals With Inherited Cancer Syndrome

This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and …

cancer of the ovary
carcinoma in situ
genetic testing
  • 23 Mar, 2022
  • 2 locations
Methods for Increasing Genetic Testing Uptake in Michigan (MiGHT)

The primary purpose of this study is to compare three interventions, two experimental and one standard of care (usual care), to see if the experimental interventions will increase the likelihood of a participant obtaining guideline-concordant genetic testing. Eligible participants will be randomized (assigned) to one of the following interventions: 1) …

cancer of the ovary
breast cancer
triple negative breast cancer
ovarian cancer
  • 16 Jun, 2022
  • 1 location
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

pleural effusion
hodgkin's disease
graft versus host disease
tumor cells
  • 25 Jul, 2022
  • 106 locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

metastatic disease
protease inhibitor
  • 08 Aug, 2022
  • 909 locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

squamous cell carcinoma
tumor cells
  • 08 Aug, 2022
  • 1029 locations
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions

Pulmonary arterial hypertension (PAH) in patients with congenital heart disease (CHD) is associated with considerable morbidity and even mortality. Next to environmental risk factors, the investigators believe that there is an important role of genetic predisposition to develop PAH in CHD. There often is a discrepancy between the severity of …

early diagnosis
right heart catheterization
genetic testing
ventricular septal defect
heart disease
  • 04 Jun, 2022
  • 1 location