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Found 9 clinical trials
Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures

This trial is intended to study the safety and effectiveness of an new anti-epileptic drug (AED) on Primary Generalized Tonic-Clonic (PGTC) Seizures. Eligible Subjects will continue to take their usual AEDs and receive either cenobamate or placebo. Subjects will have a 50% chance or receiving cenobamate or placebo (sugar pill). …

  • 0 views
  • 15 Dec, 2021
  • 6 locations
Exercise for Memory Rehabilitation in Epilepsy

responsible for memory improvements, and determine if the memory benefits and brain changes are retained 6 weeks after completing the exercise intervention in people with Idiopathic generalized epilepsy (IGE

  • 0 views
  • 09 Mar, 2022
  • 1 location
Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study

This study aims to compare the efficacy and safety profile of Magnetic Seizure Therapy and Electroconvulsive therapy.

depressive disorder
depression
depressed mood
electroconvulsive therapy
  • 0 views
  • 01 Oct, 2021
  • 1 location
Deep Brain Stimulation Post Failed Vagal Nerve Stimulation (DBS post VNS)

This is a multicenter, non-blinded, patient preference comparative trial for efficacy of deep brain stimulation (DBS) on drug-resistant epilepsy compared to continued vagal nerve stimulation (VNS) optimization in children with failed VNS. The two conditions being compared are therefore DBS (treatment) versus VNS (control). Fifty (50) patients will be recruited …

seizure
epilepsy
brain stimulation
vagal nerve stimulation
  • 6 views
  • 19 Feb, 2022
  • 1 location
Sensor-Dot and Plug 'n Patch Study in Epilepsy

The investigators plan to determine whether it is possible to use a small, unobtrusive wearable device (the Sensor Dot with Plug 'n Patch system) to follow-up epilepsy in the home environment through measurement of different biosignals (EEG, ECG, EMG, motion, skin temperature, respiration and oxygen saturation) for prolonged periods in …

  • 0 views
  • 10 May, 2021
  • 1 location
Post-stroke Epilepsy: Primary Prophylaxis Study

Advance in stroke treatment have resulted in a dramatic reduction in the stroke mortality, however, the number of stroke survivors living with morbidity has increased significantly. As we know, post-stroke epilepsy has been identified as a significant clinical issue in stroke survivors and stroke is the most common cause of …

  • 0 views
  • 08 May, 2021
  • 1 location
A Study to Evaluate the Effectiveness of Perampanel as Only Add-on Treatment in Participants With Primary or Secondarily Generalized Tonic-clonic Seizures

tonic-clonic (PGTC) or secondarily generalized tonic-clonic (SGTC) seizures based on focal or idiopathic generalized epilepsy in a non-interventional (observational) setting.

epilepsy
tonic
clonic seizure
perampanel
  • 0 views
  • 25 Feb, 2022
  • 21 locations
Detecting Absence Seizures Using Eye Tracking

The goal of this study is to develop a comfortable system that uses a wearable eye-tracker similar to eyeglasses to assist people with epilepsy in counting and measuring the severity of seizures. Participants will wear an eye-tracker during a routine EEG.

seizure
electroencephalogram
  • 31 views
  • 16 Dec, 2021
  • 5 locations
Brivaracetam: a Prospective and Multicentre Post-marketing Observational Study

, will be approached to participate in the study. The investigators will exclude individuals with generalized epilepsy as those aged less than 18 years, in order to respect current Health Canada

antiepileptics
convulsive seizure
neurological disorder
brivaracetam
generalized seizure
  • 48 views
  • 30 Sep, 2021
  • 1 location