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Found 9 clinical trials
Clinic to Community© Program for Adults With Epilepsy Admitted to Emergency Departments (C2CEDRCT)

Analysis of emergency department (ED) visits with a billing code for 'epilepsy' or 'seizure' found up to 37% are eligible for deferral. This study is a randomized controlled trial (RCT) of the Clinic To Community© program (C2C) as an intervention for adults with epilepsy visiting emergency departments at a mid …

  • 0 views
  • 13 Jun, 2022
  • 1 location
Randomized, Double-Blind Study to Evaluate Efficacy and Safety of Cenobamate Adjunctive Therapy in PGTC Seizures

This trial is intended to study the safety and effectiveness of an new anti-epileptic drug (AED) on Primary Generalized Tonic-Clonic (PGTC) Seizures. Eligible Subjects will continue to take their usual AEDs and receive either cenobamate or placebo. Subjects will have a 50% chance or receiving cenobamate or placebo (sugar pill). …

  • 0 views
  • 03 Jun, 2022
  • 6 locations
Exercise for Memory Rehabilitation in Epilepsy

responsible for memory improvements, and determine if the memory benefits and brain changes are retained 6 weeks after completing the exercise intervention in people with Idiopathic generalized epilepsy (IGE

  • 0 views
  • 09 Mar, 2022
  • 1 location
Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study

This study aims to compare the efficacy and safety profile of Magnetic Seizure Therapy and Electroconvulsive therapy.

depressive disorder
electroconvulsive therapy
depression
depressed mood
  • 0 views
  • 01 Oct, 2021
  • 1 location
Deep Brain Stimulation Post Failed Vagal Nerve Stimulation (DBSpostVNS)

This is a multicenter, non-blinded, patient preference comparative trial for efficacy of deep brain stimulation (DBS) on drug-resistant epilepsy compared to continued vagal nerve stimulation (VNS) optimization in children with failed VNS. The two conditions being compared are therefore DBS (treatment) versus VNS (control). Fifty (50) patients will be recruited …

vagal nerve stimulation
epilepsy
seizure
brain stimulation
  • 6 views
  • 24 May, 2022
  • 1 location
Sensor-Dot and Plug 'n Patch Study in Epilepsy

The investigators plan to determine whether it is possible to use a small, unobtrusive wearable device (the Sensor Dot with Plug 'n Patch system) to follow-up epilepsy in the home environment through measurement of different biosignals (EEG, ECG, EMG, motion, skin temperature, respiration and oxygen saturation) for prolonged periods in …

generalized epilepsy
seizure
epileptic syndromes
tonic
  • 4 views
  • 07 Jun, 2022
  • 1 location
Severity: Quantifying the Severity of Generalized Tonic-clonic Seizures (GTCS) With Connected Devices

By bringing together the fields of seizure detection and that of Sudden Unexpected Death in Epilepsy (SUDEP), the current project aims at delineating which set of biosensors and related biomarkers would optimally characterize the severity of GTCS and the associated risk of SUDEP.

  • 0 views
  • 09 Aug, 2022
  • 1 location
Human Epilepsy Project 3 (HEP3)

By carrying a careful, large-scale and ambitious prospective study of a cohort of participants with generalized epilepsy, the study team hopes to clarify the likelihood of response and remission

  • 0 views
  • 28 May, 2022
  • 15 locations
A Study to Evaluate the Effectiveness of Perampanel as Only Add-on Treatment in Participants With Primary or Secondarily Generalized Tonic-clonic Seizures

tonic-clonic (PGTC) or secondarily generalized tonic-clonic (SGTC) seizures based on focal or idiopathic generalized epilepsy in a non-interventional (observational) setting.

epilepsy
perampanel
clonic seizure
tonic
  • 0 views
  • 25 Feb, 2022
  • 21 locations