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Found 522 clinical trials
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A Randomized Controlled Trial of Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN Trial)

A Randomized Controlled Trial of Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN Trial)

  • 23 Nov, 2020
  • 1 location
Driving Pressure During General Anesthesia for Open Abdominal Surgery (DESIGNATION)

The purpose of this international multicenter, patient and outcome-assessor blinded randomized controlled trial is to determine whether the application of an individualized high PEEP strategy, aiming at avoiding an increase in the driving pressure during intraoperative ventilation, protects against the development of postoperative pulmonary complications.

  • 11 Mar, 2022
  • 19 locations
Miller Blade for Intubation in Adults

The study compares laryngeal view obtained with standard Macintosh blade laryngoscope and Miller blade laryngoscope in adult patients. After introduction to general anesthesia anesthesiologist

  • 04 Oct, 2022
  • 1 location
First Attempt Intubation Rate With Airtraq vs Macintosh Direct Laryngoscope (FAIRAiM)

the Macintosh direct laryngoscope in patients requiring general anesthesia for elective operation, with the aims to examine the feasibility of a large multicentre effectiveness trial by assessing

endotracheal intubation
  • 17 Feb, 2022
Incidence of Intraoperative Awareness in Indian Patient Population

The profiling of bi-spectral index (BIS) monitored facilitation of general anesthesia (GA), including, anesthesia induction and maintenance of GA depth state, emergence characteristics, and

  • 28 May, 2022
  • 4 locations
Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery

tumor surgery, bile duct surgery, thoracic surgery or orthopedic surgery and so on under general anesthesia, and the estimated operation time≥ 2 hours. Sample size: Enroll 1700 patients (850

major surgery
orthopedic surgery
mechanical ventilation
postoperative complication
  • 07 Oct, 2022
  • 1 location
A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing (PRAETORIAN-DFT)

This study will test the hypothesis that implantation of a subcutaneous implantable cardioverter defibrillator (S-ICD) without performing a defibrillation test is non-inferior to S-ICD implant with a defibrillation test with regards to the primary endpoint failed first shock in a spontaneous arrhythmia episode when implant position is confirmed with PRAETORIAN …

  • 03 Mar, 2022
  • 32 locations
EEG Guidance of Anesthesia (ENGAGES-CANADA) (ENGAGES)

This study examines the potential link between deep levels of anesthesia and delirium.

  • 24 Feb, 2022
  • 1 location
Effect of Intravenous S-ketamine on Opioid Consumption

Female patients with an American Society of Anesthesia (ASA) physical status I-II, scheduled for elective breast cancer surgery will be included in the study. Subjects will be randomly assigned to one of three groups: the placebo group, the low-dose S-ketamine group, and the high-dose S-ketamine group. The primary outcome is …

  • 04 Oct, 2022
  • 1 location
The Role of Emotional and Orientation Support in Prevention of Postoperative Delirium Among Elderly Surgical Patients

Postoperative delirium is common and associated with significant adverse outcomes. Its etiology is unknown, and little is known about associated risk factors. The investigatorea aim to test whether providing emotional and orientation support can reduce the risk of postoperative delirium in elderly patients undergoing elective non-cardiac surgery. Specifically, the investigators …

  • 28 Jun, 2022
  • 1 location