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Found 6 clinical trials
A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

patients with Angelman syndrome. Up to 20 patients (male and female) 4 and 17 years of age with a genetically confirmed diagnosis of full maternal UBE3A gene deletion (within 15q11.2-q13 region) will be

  • 0 views
  • 24 Sep, 2021
  • 6 locations
Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

This phase II trial studies how well olaparib works in treating patients with biliary tract cancer that has spread to other places in the body (metastatic) and with aberrant DNA repair gene mutations. Olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell …

measurable disease
palb2
absolute neutrophil count
olaparib
hysterectomy
  • 0 views
  • 15 Mar, 2021
  • 4 locations
Quizartinib Decitabine and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

This phase I/II trial studies how well quizartinib, decitabine, and venetoclax work in treating participants with acute myeloid leukemia or high risk myelodysplastic syndrome that is untreated or has come back (relapsed). Quizartinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. …

flt3 internal tandem duplication
decitabine
neoadjuvant therapy
cancer
cytotoxic agents
  • 11 views
  • 22 Aug, 2021
  • 1 location
Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

This phase II trial studies how well venetoclax and decitabine work in treating participants with acute myeloid leukemia that has come back or does not respond to treatment, or with high-risk myelodysplastic syndrome that has come back. Drugs used in chemotherapy, such as venetoclax and decitabine, work in different ways …

myeloid leukemia
myelomonocytic leukemia
decitabine
hydroxyurea
cancer
  • 48 views
  • 25 Jan, 2021
  • 2 locations
Method of Genetic Analysis in Genodermatoses

The goal of the study is to develop a method of genetic diagnosis in two stages, by mendelioma then by genome and transcriptome on fibroblast culture, in genodermatoses and rare diseases with cutaneous expression in the child.

  • 0 views
  • 23 Jan, 2021
  • 1 location
Gene Biobank of Sports Injuries

Preserve biological samples and gene extracts of all sports medicine-related diseases. To study related gene mutation sites and regulation. To study related molecular mechanisms and signaling pathways. A storage platform for sports medicine-related diseases research sample database has been established.

  • 0 views
  • 19 Aug, 2021
  • 1 location