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Found 20 clinical trials
International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia (Myechild01)

The main purpose of this study is : To establish which number of doses of gemtuzumab ozogamicin (up to a maximum of 3 doses) is tolerated and can be safety delivered in combination

blast cells
gemtuzumab
daunorubicin
mitoxantrone
flow cytometry
  • 0 views
  • 26 Jan, 2022
  • 69 locations
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

leukemia with or without FLT3 mutations. Drugs used in chemotherapy, such as daunorubicin, cytarabine, and gemtuzumab ozogamicin, work in different ways to stop the growth of cancer cells, either by

blast cells
cell transplantation
gemtuzumab
daunorubicin
mitoxantrone
  • 141 views
  • 10 May, 2022
  • 98 locations
Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

The trial is open to all patients with a diagnosis of acute promyelocytic leukemia (APL) who are PCR-positive for the PML-RAR transcript and less than 18 years of age.

  • 0 views
  • 21 Mar, 2021
  • 29 locations
CPX-351 and Gemtuzumab Ozogamicin in Treating Patients With Relapsed Acute Myeloid Leukemia

This phase Ib trial studies the best dose of gemtuzumab ozogamicin when given together with CPX-351 in treating patients with acute myeloid leukemia that has come back after it was previously in

blast cells
serum bilirubin level
cancer
gemtuzumab
cytarabine
  • 1 views
  • 27 May, 2022
  • 1 location
Talazoparib and Gemtuzumab Ozogamicin for the Treatment of CD33 Positive Relapsed or Refractory Acute Myeloid Leukemia

This phase I/Ib trial studies the side effects and best dose of talazoparib given together with gemtuzumab ozogamicin and to see how well they work in treating patients with CD33 positive acute

  • 0 views
  • 11 Jul, 2022
  • 2 locations
Fractionated Gemtuzumab Ozogamicin Followed by Non-engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia

. Researchers are studying whether the drug Gemtuzumab Ozogamicin, followed by an infusion of blood cells called leukocytes from a donor, can stimulate the immune system to potentially fight the leukemia

gemtuzumab
acute leukemia
refractory acute myeloid leukemia (aml)
leukapheresis
cancer
  • 3 views
  • 15 May, 2022
  • 1 location
Tretinoin and Arsenic Trioxide With or Without Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia

This phase II trial studies how well tretinoin and arsenic trioxide with or without gemtuzumab ozogamicin works in treating patients with previously untreated acute promyelocytic leukemia. Drugs

arsenic
cancer
gemtuzumab ozogamicin
idarubicin
PCR test
  • 26 views
  • 30 May, 2022
  • 5 locations
A Phase 2 Trial of Fractionated Gemtuzumab Ozogamicin to Eradicate Measurable Residual Disease in Acute Myeloid Leukemia Patients (GO for MRD)

This phase II trial studies the how well fractionated gemtuzumab ozogamicin works in treating measurable residual disease in patients with acute myeloid leukemia. Gemtuzumab ozogamicin is a

blast cells
leukemia
gemtuzumab
PCR test
acute promyelocytic leukemia
  • 5 views
  • 15 Sep, 2022
  • 1 location
Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

This phase II trial studies the side effects and how well liposome-encapsulated daunorubicin-cytarabine and gemtuzumab ozogamicin work in treating patients with acute myeloid leukemia that has

leukemia
myelomonocytic leukemia
refractory acute myeloid leukemia (aml)
daunorubicin
monoclonal antibodies
  • 14 views
  • 16 Jun, 2022
  • 1 location
Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

This phase II trial studies the side effects and how well fludarabine phosphate, cytarabine, filgrastim-sndz, gemtuzumab ozogamicin, and idarubicin hydrochloride work in treating patients with

blast cells
leukemia
gemtuzumab
colony stimulating factor
anemia
  • 24 views
  • 09 Aug, 2022
  • 1 location