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Found 362 clinical trials
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A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302)

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or

metastatic cancer
cancer
primary cancer
FGFR2
  • 173 views
  • 25 Aug, 2021
  • 146 locations
featured
CALGB 90601: A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients with Advanced Transitional Cell Carcinoma

CALGB 90601: A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients with Advanced Transitional Cell Carcinoma

  • 176 views
  • 08 Nov, 2020
  • 1 location
Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)

The purpose of this Phase II study is to assess the efficacy and safety of NIS793 with and without spartalizumab in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel

  • 0 views
  • 16 Sep, 2021
  • 25 locations
Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

(PLND) compared with the current standard of care (neoadjuvant chemotherapy [gemcitabine plus cisplatin] and RC + PLND) for participants with MIBC who are cisplatin-eligible. The dual primary hypotheses

  • 0 views
  • 26 Sep, 2021
  • 77 locations
Comparing Study Between Concurrent Chemoradiation and New Combination Treatment in Cervical Cancer Patients

The purpose of this study is: to compare the effectiveness between the new strategy of treatment (given cis-platinum plus gemcitabine-neoadjuvant chemotherapy followed by

concurrent chemoradiation
cancer
gemcitabine
adenocarcinoma
carcinoma
  • 12 views
  • 08 Nov, 2020
  • 1 location
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients in this study will have …

pembrolizumab
metastatic urothelial carcinoma
gemcitabine
systemic therapy
enfortumab vedotin
  • 9 views
  • 24 Sep, 2021
  • 114 locations
Pazopanib vs. Pazopanib Plus Gemcitabine

This study is a prospective, randomized, open-label, multicenter phase II trial in order to determine progression-free survival of patients with refractory or relapsed metastatic uterine leiomyosarcomas or other metastatic uterine tumours.

  • 2 views
  • 28 Jan, 2021
  • 16 locations
Avelumab/Gemcitabine in Sarcomatoid RCC

To determine the feasibility and safety of avelumab and gemcitabine combination therapy in patients with metastatic sRCC.

  • 4 views
  • 02 Aug, 2021
  • 1 location
Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

The study is a multi-center, un-blinded, randomized control study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.

  • 50 views
  • 28 Jun, 2021
  • 49 locations
Nab-paclitaxel and Gemcitabine in Metastatic Pancreatic Cancer

This is a single arm, open-label Phase II clinical trial to Evaluate the Efficacy and Safety of the Combination of Nab-paclitaxel and Gemcitabine in Treating Patients with metastatic pancreatic

  • 0 views
  • 22 Jan, 2021
  • 1 location