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Found 26 clinical trials
Synergistic Effect of Elemene Plus TKIs Compared With TKIs in EGFR-mutated Advanced NSCLC:Retrospective Study (SELECT-1)

This is a nationwide, multicenter and retrospective cohort study. The purpose of this study is to evaluate the synergistic effect and safety of Elemene plus TKIs in EGFR-mutated advanced non-small cell lung cancer.

EGFR
lung carcinoma
  • 0 views
  • 15 Mar, 2022
  • 17 locations
A Retrospective Pharmacogenomics Research of EGFR-TKIs Gefitinib and Erlotinib in NSCLC Patients Treatment

detection and gefitinib and erlotinib administration based on EGFR-TKIs sensitive mutations.From clinical points of view ,individual differences often occur between different patients, leading diverse

erlotinib
lung carcinoma
crizotinib
EGFR
gefitinib
  • 4 views
  • 26 Jan, 2021
  • 1 location
A Real-world Study of Adjuvant Therapy in Early Stage NSCLC With EGFR Mutation-Positive in China

This study is a prospective, national, multi-center, non-interventional study. The main purpose is to explore the initial adjuvant treatment pattern after radical resection for early-stage NSCLC patients with EGFR Mutation-Positive in the real world. The secondary purpose was to observe the postoperative follow-up treatment pattern and its subgroups (based on …

  • 0 views
  • 14 Apr, 2021
  • 50 locations
Real World Study on Erlotinib/Gefitinib Combined With Bevacizumab in Advanced Non-aquamous Non-small Cell Lung Cancer

This study aims to explore the efficacy and safety of Erlotinib/Gefitinib combined with bevacizumab in the real world for advanced non-squamous cell lung cancer with EGFR mutation, explore new

erlotinib
bevacizumab
lung carcinoma
EGFR
gefitinib
  • 6 views
  • 14 Mar, 2022
  • 1 location
Osimertinib for Advanced EGFR-positive NSCLC Patients

EGFR-TKIs gefitinib and erlotinib bind competitively to the ATP-binding site of EGFR TK domain. This binding in second-generation TKI afatinib is irreversible. These drugs have improved better outcome

tyrosine
erlotinib
afatinib
lung carcinoma
osimertinib
  • 0 views
  • 16 Sep, 2021
  • 1 location
Resistance to the Tyrosine Kinase Inhibitor Osimertinib and Pharmacokinetics in Non-small Cell Lung Cancer (RESISTYR)

compared to TKIs of previous generations (erlotinib, gefitinib). However, the response to osimertinib is heterogeneous and some patients are poor responder. In addition, even when an initial response to

  • 0 views
  • 09 May, 2022
  • 1 location