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Found 6 clinical trials
Efficacy of RIVAstigmine on Motor, Cognitive and Behavioural Impairment in Progressive Supranuclear Palsy (RIVA-PSP)

persons in France. PSP is characterised by a doparesistant parkinsonism with axial signs such as early gait instability and falls, oculomotor signs such as a vertical gaze palsy, dysphagia and dysarthria

donepezil
parkinson's disease
screening procedures
parkinsonism
dopa
  • 203 views
  • 09 Aug, 2022
  • 1 location
TReatment Strategy In Acute Ischemic larGE Vessel STROKE: Prioritize Thrombolysis or Endovascular Treatment (TRIAGE)

Should we prioritize thrombectomy or thrombolysis in acute stroke? Finding the answer to this question will improve treatment and outcome for stroke patients only by changing triage and transportation. And it will have implications for stroke patients around the world. The investigators propose a national investigator-driven, multi-center, randomised single-blinded clinical …

ischemic stroke
acute stroke
thrombectomy
  • 4 views
  • 15 Feb, 2022
  • 1 location
Mobility in Atypical Parkinsonism: a Trial of Physiotherapy (Mobility_APP)

for these patients, we will examine the effect of two types of physiotherapy in patients with multiple system atrophy (MSA), progressive supranuclear gaze palsy (PSP) and idiopathic Parkinson's

antiparkinsonian agents
parkinson's disease
parkinsonism
gaze palsy
atrophy
  • 0 views
  • 26 Jan, 2022
  • 1 location
Evaluation of the Efficacy of a Two-week EMST on Dysphagia in Parkinsonian Patients (EMST-PS)

This is an interventional therapy study designed to evaluate the efficacy of a two-week intervention, i.e. training with a specialized exhalation training device (called expiratory muscle strength training; EMST150 or EMST75; Aspire Products, Gainsville, FL) on swallowing function in patients with neurodegenerative Parkinsonian disorders. This study involves a routine endoscopic …

parkinson's disease
gaze palsy
atrophy
  • 0 views
  • 19 Apr, 2022
  • 2 locations
Genetic Studies of Strabismus Congenital Cranial Dysinnervation Disorders (CCDDs) and Their Associated Anomalies

The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.

  • 354 views
  • 19 Sep, 2021
  • 1 location
Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C

This study will evaluate clinical and laboratory tests that might be useful in determining if an investigational drug can slow the progression of Niemann-Pick Disease, Type C (NPC), a genetic disorder that results in progressive loss of nervous system function. The study will: look for a clinical or biochemical marker …

Accepts healthy volunteers
  • 28 views
  • 08 Aug, 2022
  • 1 location