Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 2511 clinical trials
Immune Modulation by Enhanced vs Standard Prehabilitation Program Before Major Surgery

Over 30 million surgeries are performed annually in the US. Up to 30% of surgical patients experience delayed surgical recovery, marked by prolonged post-surgical pain, opioid consumption, and functional impairment, which contributes $8 billion annually to US health care costs. Novel interventions that improve the resolution of pain, minimize opioid …

abdominal surgery
anesthesia
abdominal operation
opioid
major surgery
  • 0 views
  • 06 Dec, 2021
  • 1 location
CCRT With Itraconazole in Locally Advanced Squamous Esophageal Cancer

The objective of this study is to evaluate the efficacy and safety of concurrent chemoradiotherapy combined with Itraconazole in patients with locally adcvanced esophageal squamous cancer

esophageal squamous cell carcinoma
esophagus cancer
cancer
chemoradiotherapy
measurable disease
  • 0 views
  • 26 Jan, 2021
  • 1 location
Circulating Tumor DNA Analysis to Optimize the Operative and Postoperative Treatment for Patients With Colorectal Cancer - Intervention Trial 2

IMPROVE-IT2 is a randomized multicenter trial comparing the outcomes of ctDNA guided post-operative surveillance and standard-of-care CT-scan surveillance. The hypothesis of this study is that ctDNA guided post-operative surveillance combining ctDNA and radiological assessments could result in earlier detection of recurrent disease and identify more patients eligible for curative treatment.

rectal carcinoma
adjuvant chemotherapy
rectal cancer
cancer
recurrent disease
  • 0 views
  • 25 Jan, 2021
  • 1 location
Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction

Our main objective is to evaluate the effect of Ocoxin-Viusid on the quality of life of patients with advanced stomach cancer and esophagogastric junction. The Ocoxin-Viusid nutritional supplement is expected to improve quality of life and tolerance to treatment with Chemotherapy.

blood cell count
adenocarcinoma
neutrophil count
ocoxin-viusid
cancer chemotherapy
  • 52 views
  • 09 Feb, 2022
  • 1 location
Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei

Appendiceal cancer is a rare disease that does not cause many symptoms. As such, doctors are not sure if chemotherapy actually has an effect on the disease. The goal of this clinical research study is to learn more about the effects that chemotherapy may have on appendiceal cancer.

cancer
systemic chemotherapy
adenocarcinoma
neutrophil count
  • 20 views
  • 23 Jan, 2021
  • 1 location
Perioperative Palliative Care Surrounding Cancer Surgery for Patients & Their Family Members (PERIOP-PC)

The study goal is to compare surgeon-palliative care team co-management, versus surgeon alone management, of patients and family members preparing for major upper gastrointestinal cancer surgery. The study also aims to explore, using qualitative methods, the impact of surgeon-palliative care team co-management versus surgeon alone management on the perioperative care …

cancer
carcinoma
  • 2 views
  • 14 Feb, 2022
  • 5 locations
Ulixertinib (BVD-523) and Hydroxychloroquine in Patients w Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas (UTAH)

Open-label dose escalation of Ulixertinib combined with fixed dose of hydroxychloroquine.

KRAS
adenocarcinoma
liver metastasis
cancer
metastasis
  • 0 views
  • 13 Mar, 2022
  • 1 location
Study of Combination Therapy With the MEK Inhibitor Cobimetinib Immune Checkpoint Blockade Atezolizumab and the AUTOphagy Inhibitor Hydroxychloroquine in KRAS-mutated Advanced Malignancies

This research study is for patients with an advanced cancer that carries a mutation in a gene called KRAS. Genes are parts of our DNA which carry instructions for a cell (the smallest component of an body part). In many cancers, the KRAS gene contains errors (mutations) which allows the …

cobimetinib
KRAS
adenocarcinoma
immunoglobulin
fluorouracil
  • 0 views
  • 02 Nov, 2021
  • 1 location
Impact Of Nurse Navigation Program on Outcomes in Patients With GI Cancers (ACCESS)

The purpose of this study is to learn about the impact of the Oncology Nurse Navigation program on the frequency of Emergency Department, urgent care visits and inpatient hospital admissions; and overall survival rate at 6 months. The investigators aim to understand if prompt and effective coordination of care provided …

cancer
5-fluorouracil
oxaliplatin
capecitabine
  • 0 views
  • 01 May, 2022
  • 1 location
A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

The purpose of this study is to evaluate the clinical activity of gemcitabine, nab-paclitaxel, capecitabine, cisplatin, and irinotecan (GAX-CI) in patients with metastatic pancreatic cancer.

adenocarcinoma
capecitabine
metastatic pancreatic adenocarcinoma
primary cancer
administration intravenous
  • 81 views
  • 10 Mar, 2022
  • 1 location