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Found 85 clinical trials
Examining the Effect of Ondansetron on Bowel Prep Success

This is a pilot randomized-controlled trial assessing the utility of ondansetron for improving pediatric pre-colonoscopy bowel prep outcomes using the boston bowel preparation score, as well as assessing the impact on patient experience of bowel preparation.

  • 10 Jul, 2022
  • 1 location
Low Dose Versus Normal Dose Ketorolac for Postoperative Pain After Prostatectomy and Hysterectomy

A monocenter, prospective, double-blind, randomized controlled non-inferiority trial will be designed to investigate if ketorolac 10 mg is as effective for pain relief as the standard dose of 30 mg in patients undergoing robot assisted radical prostatectomy (RARP) or hysterectomy by laparoscopic assisted vaginal hysterectomy (LAVH) or total laparoscopic hysterectomy …

postoperative pain
pain relief
  • 06 May, 2022
  • 1 location
Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis

The purpose of this study is to investigate the safety and efficacy of early administration of two different doses of dexamethasone in high risk septic patients.

lactate level
systolic blood pressure
blood lactate
  • 21 Mar, 2022
  • 2 locations
Tranexamic Acid During Colonic Endoscopic Resection Procedures

Colonoscopy with polypectomy reduces the incidence and mortality associated with colon cancer. However, polypectomy is associated with adverse events such as bleeding. Tranexamic acid (TXA) is a synthetic derivative of lysine that exerts antifibrinolytic effects and may prevent bleeding. The investigators aim to evaluate the effect of local TXA on …

  • 08 Aug, 2022
  • 1 location
Magnetic Compression Anastomosis for Recanalization of Biliary Stricture

Biliary stricture is a common complication after end-to-end biliary anastomosis, especially after liver transplantation. This study is designed to investigate the safety and efficacy of magnetic recanalization technique, a newly clinical method, for treating biliary anastomotic stricture.

  • 27 May, 2022
  • 1 location
Study of Atezolizumab and Bevacizumab With Y-90 TARE in Patients With Unresectable Hepatocellular Carcinoma (HCC)

This is an open-label, multi-center, randomized phase II study comparing the Y90 TARE followed by bevacizumab and atezolizumab treatment to the Y90 TARE treatment alone in unresectable advanced stage HCC.

  • 28 Jul, 2022
  • 6 locations
Therapeutic Effects of Traditional Chinese Medicine in Topical Use on Upper Extremities Fracture

There is no study evaluating the clinical effect of traditional chinese medicine(TCM) in topical use on musculotendinous injury, nor is that investigating the effectiveness on bone fracture healing. We hypothesize that with aid of topical chinese herbal medicine in addition to oral analgesics can be more beneficial in treating post …

  • 26 Jan, 2021
  • 1 location
Fecal Microbiota Transplantation for Steroid Resistant/Dependent Acute GI GVHD (FEMITGIGVHD)

The purpose of this study is to evaluate the efficacy and safety of fecal microbiome transplantation in patients with steroid resistant/dependent acute gastrointestinal graft-versus-host disease (GVHD). The patient will cease antibiotics treatment 1 day before FMT, and stop taking food 6 hours before FMT. Patients will be given Ondansetron intravenously …

hematologic disorders
cell transplantation
blood disorder
graft versus host disease
  • 04 Mar, 2022
  • 2 locations
IBD Neoplasia Surveillance Pilot RCT (IBDDysplasia)

To determine if random biopsies can be safely eliminated from screening of average risk persons with IBD, the investigators propose to carry out a pilot randomized control trial in which targeted biopsies in combination with random biopsies will be compared to targeted biopsies alone in terms of pre-cancerous lesion capture …

primary sclerosing cholangitis
  • 11 May, 2022
  • 11 locations
Efficacy of Ticagrelor Plus Aspirin in Minor Non-cardioembolic Ischemic Stroke

This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is assess the efficacy of ticagrelor plus aspirin in reduce of minor non-cardioembolic ischemic stroke or high risk TIA …

  • 12 Sep, 2021
  • 2 locations