Found 62 clinical trials
Endoscopic Full Thickness Resection for Gastric GIST (EFTR)
This is a clinical trial to evaluate the efficacy and safety of endoscopic full thickness resection for treatment of gastric GIST
- 7 views
- 17 Mar, 2022
- 1 location
Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure
The primary objective is to compare the efficacy of lenvatinib plus Best Supportive Care versus Placebo plus Best Supportive Care in the treatment of patients with advanced GIST, after failure
- 0 views
- 09 Aug, 2021
- 8 locations
A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients With Advanced GIST
Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Substrate
- 0 views
- 15 Dec, 2021
- 2 locations
Submucosal Tumor Removal by Endoscopic Excision Therapy
to learn about the rate of so-called GIST tumors and other histologies, as well as the rate of change in the follow-up group. Also, study contents will be accuracy of endosonographic imaging
- 0 views
- 01 Jul, 2021
- 1 location
Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies
This study is a Phase Ib, multi-center, open-label study of TNO155 in combination with spartalizumab or ribociclib with a dose escalation part followed by a dose expansion part in adult subjects with advanced solid tumors. These two treatment arms will enroll subjects in parallel to characterize the safety, tolerability, PK, …
- 19 views
- 11 Apr, 2022
- 8 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
to accrual 02/06/2018) Vulvar cancer (closed to accrual) MetaPLASTIC carcinoma (of the breast) (closed to accrual) Gastrointestinal stromal tumor (GIST) (closed to accrual
- 6634 views
- 10 Aug, 2022
- 752 locations
PRecision Oncology Evidence Development in Cancer Treatment - Liquid (PREDiCTl)
The current standard of care for molecular characterization of tumors is tissue based next generation sequencing (NGS) panel. Liquid biopsies (ie blood) are of increasing interest and have been implemented as a diagnostic tool in some countries. This study compares tissue based and liquid based testing to evaluate the detection …
- 0 views
- 09 Aug, 2022
- 1 location
Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)
the treatment of SDH-Mutant/Deficient Gastrointestinal Stromal Tumor.
- 11 views
- 12 Feb, 2022
- 4 locations
A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101)
stromal tumors (GIST) who are judged to be refractory to imatinib, estimate the recommended dose, evaluate safety and pharmacokinetics, and observe the antitumor effect. Expansion part consists of 3 arms
- 0 views
- 11 Aug, 2022
- 1 location
A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
This study will assess the safety, efficacy, and pharmacokinetics of THE-630 in participants with advanced gastrointestinal stromal tumors (GIST).
- 0 views
- 28 Jul, 2022
- 6 locations