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Found 66 clinical trials
Comparison of Endoscopic and Laparoscopic Resection for Small Gastric Gastrointestinal Stromal Tumor

Comparison of Endoscopic and Laparoscopic Resection for Small Gastric Gastrointestinal Stromal Tumor

  • 0 views
  • 22 Jan, 2021
  • 1 location
Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST)

The aim of this study is to demonstrate that the use of Gleevec in initially non-resectable gastrointestinal stromal tumors can lead to allow complete resection in 20% of cases.

partial resection
metastasis
imatinib
complete resection
measurable disease
  • 6 views
  • 07 Nov, 2020
  • 1 location
Endoscopic Full Thickness Resection for Gastric GIST

This is a clinical trial to evaluate the efficacy and safety of endoscopic full thickness resection for treatment of gastric GIST

  • 3 views
  • 23 Jan, 2021
  • 1 location
Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure

The primary objective is to compare the efficacy of lenvatinib plus Best Supportive Care versus Placebo plus Best Supportive Care in the treatment of patients with advanced GIST, after failure

  • 0 views
  • 09 Aug, 2021
  • 8 locations
  • 0 views
  • 22 Aug, 2021
  • 2 locations
Salvage Therapy With Sunitinib Docetaxel and Platinum on Metastatic or Unresectable Non Small Cell Lung Cancer

completed or still ongoing. So far, the efficacy of sunitinb has been confirmed by the phase III trial for imatinib-resistance or intolerance advanced gastrointestinal stromal tumor patients. And

bevacizumab
solid tumour
neutrophil count
carcinoma
lung carcinoma
  • 2 views
  • 08 Nov, 2020
  • 1 location
Submucosal Tumor Removal by Endoscopic Excision Therapy

to learn about the rate of so-called GIST tumors and other histologies, as well as the rate of change in the follow-up group. Also, study contents will be accuracy of endosonographic imaging

  • 0 views
  • 01 Jul, 2021
  • 1 location
Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement

The purpose of this study is to verify effect and tolerability of imatinib on pulmonary and skin fibrosis in patients affected by systemic sclerosis.

scleroderma
pulmonary involvement
progressive systemic sclerosis
fibrosis
cyclophosphamide
  • 33 views
  • 07 Nov, 2020
  • 1 location
Safety Tolerability and Efficacy of Regorafenib in Combination With FOLFIRINOX in Patients With Colorectal Cancer

Safety, tolerability and efficacy of regorafenib in combination with FOLFIRINOX in patients with RAS-mutated metastatic colorectal cancer: a dose-escalation, phase I/II trial

thromboplastin
platelet count
lipase
metastasis
folfirinox
  • 1 views
  • 25 May, 2021
  • 4 locations
Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies

This study is a Phase Ib, multi-center, open-label study of TNO155 in combination with spartalizumab or ribociclib with a dose escalation part followed by a dose expansion part in adult subjects with advanced solid tumors. These two treatment arms will enroll subjects in parallel to characterize the safety, tolerability, PK, …

tno155
solid tumour
targeted therapy
progressive disease
squamous cell carcinoma of head and neck
  • 5 views
  • 01 Aug, 2021
  • 8 locations