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Found 750 clinical trials
Role of the Liver in Glucose Homeostasis Using Metabolic Imaging

The primary objective of this study is to assess hepatic glucose uptake using non-invasive metabolic imaging in three different populations that differ in terms of insulin and glucose kinetics. Between-group comparison will address the following two hypotheses: i) Hepatic glucose uptake will be lower in participants with type 1 diabetes …

  • 0 views
  • 07 May, 2021
  • 1 location
Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

The study is a prospective, observational study evaluating the utility of endoscopic ultrasound or MRI for the identification of preneoplastic and neoplastic pancreatic lesions in patients at high risk for pancreatic cancer, specifically those with BRCA1/2, ATM, or PALB2 mutations.

BRCA1
pdac
BRCA1/2
ATM
endoscopic ultrasound
  • 10 views
  • 15 Jun, 2022
  • 1 location
Ultrasound Assessment of Diaphragmatic Function in Infants With BPD

Preterm infants have high and prolonged exposure to positive pressure ventilation, which contributes to acute lung injury and the development of bronchopulmonary dysplasia (BPD). Despite the risk of diaphragmatic dysfunction in infants with BPD, the effect of prolonged ventilator support on the diaphragmatic function of preterm infants has not been …

  • 0 views
  • 14 Jun, 2022
  • 1 location
SKY Breath Intervention

Depression is highly debilitating and prevalent among adolescents. Adolescent-onset depression is associated with long, severe, and recurrent episodes that are often not responsive to treatment. There is a dire need to develop novel treatments that are efficient, cost-effective, and tolerant for this population. Sudarshan Kriya Yoga (SKY) is a breath-based …

depressed mood
Accepts healthy volunteers
anxiety
depressive disorder
moderate depression
  • 0 views
  • 30 Jun, 2022
  • 1 location
Gaucherite - A Study to Stratify Gaucher Disease

The purpose of this research is to review data already collected and to collect new data from adults and children in England with Gaucher Disease to determine clinical factors which predict severity and response to therapy of Gaucher disease especially in the areas of bone, cancer and brain conditions.

enzyme therapy
cancer
  • 117 views
  • 28 Jul, 2021
  • 8 locations
EUS Elastography for Predicting Cirrhotic-related Complications

Evaluation of the tissue stiffness as a surrogate marker of degree of liver cirrhosis has gained popularity in recent decades. Current guidelines also advocate the use of Fibroscan® machine (EchoSens, Paris, France) to detect any advanced liver fibrosis as represented by high liver stiffness, for prediction of varices development. Apart …

elastography
stiffness
varicose veins
cirrhosis
fibrosis
  • 0 views
  • 25 Mar, 2022
  • 1 location
Does NIV-NAVA Improve Diaphragmatic Function in Preterm Infants

Non-Invasive Positive Pressure Ventilation (NIPPV) provides un-synchronized positive pressure and considered to be superior to nCPAP in preventing extubation failure. Recently, Non-Invasive Ventilation Neurally-Adjusted Ventilatory Assist (NIV-NAVA) was introduced to NICU. NAVA is a ventilation mode that uses the electrical activity of the patient's diaphragm (Edi-signal) to guide both timing …

  • 0 views
  • 25 Apr, 2022
  • 1 location
Rapid Autopsy and Procurement of Cancer Tissue

Background Individuals with cancer of the lung, chest cavity, ovary, or bladder, as well as patients who have been treated with adoptive cell therapy unfortunately commonly succumb to their disease. Some agree to donate their bodies to cancer research that may help the medical community better understand these diseases. Studies …

lung carcinoma
lung cancer
cavity
urothelial carcinoma
thymoma
  • 44 views
  • 19 Jun, 2022
  • 1 location
Register Study: Implementation of Pharyngeal Electrostimulation Therapy for the Treatment of Acute Neurogenic Dysphagia (R:IphEst)

Neurogenic dysphagia occurs with disruption of neurological systems or processes involved in the execution of coordinated and safe swallowing. It is common in patients with neurological diseases, in particular in patients treated in Intensive Care Units (ICU) who are intubated (up to 62%) and / or tracheotomised (up to 83%). …

traumatic brain injury
  • 0 views
  • 23 Mar, 2022
  • 1 location
EUS-guided Through-the-needle Microforceps Biopsy Outcomes

INTRODUCTION: The diagnosis of pancreatic cystic lesions (PCLs) is increasing due to improvements of cross-sectional imaging. It is mandatory, for appropriate management, to make an accurate diagnosis and risk stratification, since some of these lesions may harbor malignancy or have potential for malignant transformation and hence surgical resection is required. …

pancreatitis
endoscopic ultrasound
cancer
fine needle aspiration
malignant transformation
  • 0 views
  • 20 Jun, 2022
  • 1 location