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Found 752 clinical trials
Trial for Application of Laparoscopic Total Gastrectomy With Lymph Node Dissection for Gastric Cancer (KLASS-06)

Although Laparoscopic gastrectomy for both early and locally advanced gastric cancer has gained popularity, the use of laparoscopic total gastrectomy for proximal advanced gastric cancer is still limited to some experienced surgeons, because of its technical difficulties in D2 lymph node dissection and anastomoses. Some retrospective and cohort studies regarding …

lymphadenectomy
metastasis
carcinoma
gastric adenocarcinoma
adenocarcinoma
  • 48 views
  • 02 Mar, 2022
  • 1 location
S-1 for 9 Months Versus 1 Year for Stage II Gastric Cancer (SMAC)

The study aims to compare the efficacy and safety of S-1 for 9 months versus S-1 for 1 year as adjuvant chemotherapy after D2 resection in patients with gastric cancer. Hypothesis: For gastric patients after D2 resection, S-1 for 9 months shows non-inferiority to S-1 for 1 year in disease-free …

adjuvant chemotherapy
adenocarcinoma
immunostimulants
cancer chemotherapy
lymphadenectomy
  • 0 views
  • 07 Feb, 2022
  • 6 locations
RCT of Gastric ESD With or Without Epineprhine Added Solution

This is an international multi-center randomised controlled study comparing outcomes of gastric endoscopic submucosal dissection (ESD) with or without addition of epinephrine in the submucosal injection solution.

epinephrine
endoscopic submucosal dissection
  • 6 views
  • 19 Feb, 2022
  • 1 location
Nab-paclitaxel Combined With S-1 as Adjuvant Chemotherapy for Stage Ⅲ Gastric Cancer

This is a randomized, open-label phase III study. The treatment was compare the efficacy and safety of Albumin-bound Paclitaxel plus S-1 versus Oxaliplatin plus capecitabine (XELOX) treating stage gastric cancer as adjuvant setting

tegafur
cancer chemotherapy
immunostimulants
xelox regimen
gastric adenocarcinoma
  • 0 views
  • 01 Mar, 2022
  • 1 location
Adjuvant Capecitabine Versus Observation Alone in Curatively Resected Stage IB Gastric Cancer((KCSG ST14-05): CATALYSIS

multi-center, prospective, randomized, open-label phase III

adenocarcinoma
renal function
adenocarcinoma of the gastroesophageal junction
immunostimulants
capecitabine
  • 11 views
  • 24 Jan, 2022
  • 1 location
Capecitabine or Observation for Patients With pT1N+M0 or pT2-3N0M0 Gastric Adenocarcinoma Undergoing R0 Resection

Gastric cancer (GC) is one of the most common and lethal malignancies in Asia. For early (stage T1) GC, it has been found by analyzing surgical specimens that ~5% of cancers have lymph node metastasis. For patients with stage T2-3N0M0 GCs, there is a considerable probability of micro-metastasis. While the …

cancer chemotherapy
immunostimulants
metastasis
adjuvant therapy
gastric adenocarcinoma
  • 0 views
  • 24 Jan, 2021
  • 1 location
Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients

This study aimed to investigate the effect of low-dose (100 mg) asprin on the prevention of gastric cancer in the early gastric cancer patients with negative H. pylori status who underwent endoscopic submucosal dissection.

early gastric cancer
endoscopic submucosal dissection
  • 0 views
  • 23 May, 2021
  • 13 locations
Oxaliplatin Combined With S-1(SOX) Neoadjuvant Chemotherapy for Different Cycles in Patients With Gastric Cancer

RESONANCE-II trial is a prospective, multicenter, randomized, controlled phase III study which will enroll 524 patients in total. Patients with eligibility will be registered, pre-enrolled and receive three cycles of SOX. Then, tumor response evaluation will be carried out. Those who achieve stable disease or progressive disease will be excluded. …

  • 0 views
  • 03 Feb, 2021
  • 1 location
Multicenter Study on Laparoscopic Total Gastrectomy for Advanced Gastric Cancer

CLASS-07 trial is a prospective, multicenter, randomized controlled trial for comparison of long-term outcomes between laparoscopic total gastrectomy (LTG) and open total gastrectomy (OTG) in patients with locally advanced gastric cancer (clinical stage T2-4aN0-3M0). The primary purpose of this study is to evaluate the overall survival and determine the efficacy …

  • 0 views
  • 05 Mar, 2021
  • 1 location
HX008 Plus Irinotecan Versus Placebo Plus Irinotecan as Second-line Treatment in Advanced Gastric Cancer

This is a randomized, double-blinded, multicenter study to evaluate the efficacy and safety of HX008 injection combined with irinotecan versus placebo combined with irinotecan as second-line therapy in patients with adcanced gastric or gastroesophageal junction (GEJ) adenocarcinoma who have had tumor progression after first-line treatment with platinum and/or fluropyrimidine therapy.

adenocarcinoma
gastric adenocarcinoma
fluoropyrimidine
metastatic adenocarcinoma
irinotecan
  • 0 views
  • 03 Feb, 2021
  • 64 locations