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Found 605 clinical trials
Adjuvant Capecitabine Versus Observation Alone in Curatively Resected Stage IB Gastric Cancer((KCSG ST14-05): CATALYSIS

multi-center, prospective, randomized, open-label phase III

adenocarcinoma
adenocarcinoma of the gastroesophageal junction
capecitabine
renal function
immunostimulants
  • 11 views
  • 24 Jan, 2022
  • 1 location
Oxaliplatin Combined With S-1(SOX) Neoadjuvant Chemotherapy for Different Cycles in Patients With Gastric Cancer

RESONANCE-II trial is a prospective, multicenter, randomized, controlled phase III study which will enroll 524 patients in total. Patients with eligibility will be registered, pre-enrolled and receive three cycles of SOX. Then, tumor response evaluation will be carried out. Those who achieve stable disease or progressive disease will be excluded. …

  • 0 views
  • 03 Feb, 2021
  • 1 location
HX008 Plus Irinotecan Versus Placebo Plus Irinotecan as Second-line Treatment in Advanced Gastric Cancer

This is a randomized, double-blinded, multicenter study to evaluate the efficacy and safety of HX008 injection combined with irinotecan versus placebo combined with irinotecan as second-line therapy in patients with adcanced gastric or gastroesophageal junction (GEJ) adenocarcinoma who have had tumor progression after first-line treatment with platinum and/or fluropyrimidine therapy.

adenocarcinoma
gastric adenocarcinoma
metastatic adenocarcinoma
irinotecan
fluoropyrimidine
  • 0 views
  • 03 Feb, 2021
  • 64 locations
A Phase III Study Comparing Total and Partial Omentectomy for Patients With Advanced Gastric Cancer

This is a phase III, multicenter, prospective, randomized, controlled clinical trial to evaluate the impact of omentectomy for advanced gastric cancer on patient survival.

  • 0 views
  • 16 May, 2021
  • 1 location
A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)

A Phase 2/3 Study of Evorpacept (ALX148) in Combination With Trastuzumab, Ramucirumab, and Paclitaxel in Patients With Advanced HER2-overexpressing gastric/GEJ adenocarcinoma.

trastuzumab
paclitaxel
erbb2
adenocarcinoma
fluoropyrimidine
  • 0 views
  • 22 Apr, 2022
  • 18 locations
Optimal Duration of Oxaliplatin in Adjuvant XELOX for Gastric Cancer Patients (EXODOX)

This study aims to compare the efficacy and safety of reduced adjuvant XELOX treatment (4 cycles of XELOX followed by 4 cycles of capecitabine alone) to standard adjuvant XELOX treatment (8 cycles of XELOX).

xelox regimen
adenocarcinoma
oxaliplatin
capecitabine
renal function
  • 0 views
  • 17 Mar, 2022
  • 1 location
Prophylactic Preoperative HIPEC in Advanced Gastric Cancer at High Risk of Peritoneal Recurrence

gastric cancer at high risk of peritoneal metastases. The impact of treatment on peritoneal recurrence and survival over 6 months, 1, 3 and 5 years will be assessed.

gastrectomy
irinotecan
cancer chemotherapy
  • 0 views
  • 03 Sep, 2021
  • 1 location
Comparison of Endoscopic Resection and Surgery for Early Gastric Cancer With Undifferentiated Histological Type

This multi-center, randomized controlled trial is designed to evaluate clinical effectiveness and cost-effectiveness of ESD for undifferentiated type of EGC meeting the expanded indication compared with surgery.

early gastric cancer
carcinoma
adenocarcinoma
endoscopic submucosal dissection
gastrectomy
  • 0 views
  • 17 Sep, 2021
  • 1 location
Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (FORTITUDE-101)

The main objective of this study is to compare efficacy of bemarituzumab combined with oxaliplatin and 5-fluorouracil (5-FU) (mFOLFOX6) to placebo plus mFOLFOX6 as assessed by overall survival (OS).

cancer chemotherapy
fluorouracil
platelet count
oxaliplatin
leucovorin
  • 0 views
  • 28 Jun, 2022
  • 107 locations
PREACT Study: Locally Advanced Gastric Cancer, Chemoradiotherapy vs. Chemotherapy Followed by D2 Surgery and Adjuvant Chemotherapy (PREACT)

Although the incidence of gastric cancer has been substantially declining for several decades, it is still the sixth most common cancer and the fourth most frequent cause of cancer death

tegafur
curative surgery
immunomodulator
gastric resection
oxaliplatin
  • 22 views
  • 24 Feb, 2022
  • 1 location