Found 95 clinical trials
Surgical or Medical Treatment (ST2OMP)
This study will test the hypothesis that metabolic bariatric surgery will be more effective at providing durable glycemic control and reduce co-morbidities than intensive medical therapy in youth with type 2 diabetes.
- 43 views
- 05 Sep, 2023
- 2 locations
Cerebrospinal Fluid Biomarkers in Bariatric Surgery
The goal of this project is to understand why bariatric surgery is such an effective treatment for obesity with a focus on brain mechanisms. Cerebrospinal fluid (CSF) neuropeptide, hormone and protein levels will be measured as a surrogate for changes in brain activity in participants before and after bariatric surgery …
- 0 views
- 14 Apr, 2022
Comparison of Gastric By-Pass and Optimized Medical Treatment in Obese Diabetic Patients
The objectives are to compare the results of the Gastric By-Pass (GBP) to that of optimized medical therapy in patients with obesity and poorly controlled type 2 diabetes in terms of mortality, weight loss, glycemic control, quality of life, cost, cost-effectiveness and cost utility of these two strategies.
- 72 views
- 25 Jan, 2021
- 13 locations
Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage
The primary objective is to evaluate the efficacy and assess the role of Porcine Fibrin Sealant (Bioseal®) in preventing cervical anastomotic leakage after esophagectomy in the patients with resectable thoracic esophageal cancer and gastroesophageal junction cancer.
- 0 views
- 06 May, 2022
- 6 locations
Surgical Innovation for Diabetes Treatment 2
This study aims to understand the enteroendocrine physiological changes in superobese patients submitted to two different bariatric procedures (biliopancreatic diversion with duodenal switch versus single anastomosis duodeno-ileal bypass), when perfomed as primary or revisional surgeries (after a sleeve gastrectomy). The main purpose is to establish the metabolic changes obtained with …
- 0 views
- 04 Oct, 2022
- 2 locations
Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 3 (PBH Forecast)
The overall aim of this study is to prevent hypoglycemic events in patients with hypoglycemia after a meal and to develop a sustainable hypoglycemia correction strategy.
- 0 views
- 27 Aug, 2023
- 1 location
Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care (DiabOUT)
This study is a randomized trial that evaluates the effect of metformin addition or not to standard care on the duration of diabetes remission after bariatric surgery.
- 0 views
- 27 May, 2022
- 12 locations
Sleeve Gastrectomy With Reestablishment of the Acute Angle of His (SG-REACH) in Obese Patients (SG-REACH)
Gastroesophageal reflux disease (GERD) is one of the most common chronic conditions that can affect one's quality of life. Laparoscopic sleeve gastrectomy (LSG) has become a popular technique and currently is the most frequently practiced surgical operation to treat obesity today. However, the prevalence of GERD following SG can be …
- 0 views
- 04 Oct, 2022
- 1 location
Testosterone in Bariatric Patients
Bariatric surgery is an effective method in the treatment of severe obesity and type 2 diabetes mellitus achieving high remission rates. However, weight loss also causes loss of skeletal muscle and bone mass which at least partly could be prevented by exercise and dietary intervention although the counselling of obese …
- 14 views
- 04 Oct, 2022
- 1 location
Bariatric Surgery Observation Study Part 2 (BAROBS2)
The goal of this observational study is to explore the longterm effects of two bariatric surgical procedures by inviting patients from three public hospitals who had Roux-en-Y gastric bypass or
- 0 views
- 11 Apr, 2023
- 1 location