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Found 219 clinical trials
Effect of Bariatric Surgery Versus Medical Therapy on Metabolic Syndrome (EBSMTMS)

Bariatric surgery (BS) is known to improve the components of metabolic syndrome (MS) in obese patients. However, few studies have evaluated the impact of bariatric surgery versus medical therapy (MT) in patients with MS, especially in patients with low body mass index (BMI). This study aimed to assess the effect …

body mass index
cardiovascular disease
  • 25 May, 2022
Long Term Effects of Weight Loss on Post-prandial Gut Hormone Responses and Meal Induced Thermogenesis

A study to examine post-prandial gut-hormone secretion, meal-induced thermogenesis, fasting plasma metabolomic/lipidomic and cardiovascular indices among surgically managed obese individuals in the long term compared to conservatively managed obese patients.

  • 18 Feb, 2022
  • 1 location
Role of the Liver in Glucose Homeostasis Using Metabolic Imaging

The primary objective of this study is to assess hepatic glucose uptake using non-invasive metabolic imaging in three different populations that differ in terms of insulin and glucose kinetics. Between-group comparison will address the following two hypotheses: i) Hepatic glucose uptake will be lower in participants with type 1 diabetes …

  • 07 May, 2021
  • 1 location
Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial) (SWIFT)

The purpose of the SWIFT Trial is to answer two research questions. Does bariatric surgery before total knee arthroplasty (TKA) improve both perioperative and long-term outcomes of TKA in extreme obesity? Does bariatric surgery before TKA delay or possibly negate the need for arthroplasty?

body mass index
bariatric surgery
joint reconstruction
  • 15 Mar, 2022
  • 1 location
Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 1 (PBH Forecast)

The overall aim of this study is to prevent hypoglycemic events in patients with hypoglycemia after a meal and to develop a sustainable hypoglycemia correction strategy.

  • 17 Mar, 2022
  • 1 location
Trends and Safety in Revisional Bariatric Surgery in Italy

Background: Revisional bariatric surgery (RBS) represents a further solution for patients who experience an inadequate response following initial bariatric surgery or significant weight regain following an initial satisfactory response. Studies including the follow-up of patients with complications after RBS are still lacking. Aim: to analyze the trend, mortality, and complications …

  • 23 Mar, 2022
  • 6 locations
Bariatric Endoscopy for Treatment of Obesity

A single-center prospective, randomized controlled study will be conducted in order to compare the main bariatric endoscopy (BE) techniques in I and II grade obese patients (BMI >30 kg/m2) at Gastroenterology and Gastrointestinal Endoscopy Unit, Mater Olbia Hospital, Qatar Foundation Endowment & Gemelli Foundation, Italy in period June 2020 - …

  • 15 Jun, 2022
  • 1 location
Impact of Undernutrition Definitions on Its Prevalence in Hospitalized Patients (PROTEIN)

In France, the prevalence of undernutrition among hospitalized patients varies from 30 to 50%. Undernutrition is strongly associated with a decrease in the patient's functional capacities and an increase in morbidity and mortality and in healthcare costs. In 2019, the Global Leadership Initiative on Malnutrition (GLIM) and the Haute Autorité …

  • 27 Apr, 2022
  • 1 location
Photographic Food Recognition and Meal Size Estimation Before and After Roux-en-Y Gastric Bypass

Direct measurements of changes in food selection in humans after RYGB have been limited by the unreliability of patients, which poses significant methodological and conceptual challenges to researchers and study design. Self-monitoring requires time and effort, and many find tracking of dietary intake tedious, which contributes to attrition. Direct measurements, …

Accepts healthy volunteers
  • 23 May, 2022
  • 1 location