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Found 16 clinical trials
Randomized Trial of Sedative Choice for Intubation (RSI)

Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, but the optimal sedative medication for intubation of critically ill adults remains …

  • 0 views
  • 04 Oct, 2022
  • 1 location
A First-In-Human (FIH) Study of Inhibitory Interneurons (NRTX- 1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)

This clinical trial is designed to test whether a single stereotactic intracerebral administration of inhibitory nerve cells into subjects with drug-resistant mesial temporal lobe epilepsy is safe (frequency of adverse events) and effective (seizure frequency).

  • 0 views
  • 11 Oct, 2022
  • 8 locations
The Role of the Microbiota-gut-brain Axis in Brain Development and Mental Health

The role of the microbiota-gut-brain axis in brain development and mental health

Accepts healthy volunteers
  • 98 views
  • 03 Mar, 2022
  • 1 location
  • 0 views
  • 22 Oct, 2022
  • 1 location
A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans

neurotransmitter, gamma aminobutyric acid (GABA). This novel approach is complimentary to the use of antidepressant medications that primarily target the monoamine systems. Low activity in the PNS and GABA systems

major depressive disorder
remission
hdrs
depression
behavior modification
  • 21 views
  • 01 Feb, 2022
  • 1 location
Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

Background Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Researchers think brain development may be controlled by gamma-aminobutyric

Accepts healthy volunteers
  • 33 views
  • 04 Oct, 2022
  • 1 location
Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

), which was shown to be one of the mechanisms of tDCS effects, the other being changes in the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Therefore, to address the above question

neurodegenerative disorders
alzheimer's disease
Accepts healthy volunteers
  • 42 views
  • 14 Jul, 2022
  • 1 location
Effect of GABA on ADHD and Seizures in Children With Epilepsy.

Effect of GABA on ADHD and seizures in Children with epilepsy.

seizure
  • 13 views
  • 16 Feb, 2022
  • 1 location
Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Background Magnetic resonance imaging (MRI) is a widely used scanning technique to obtain images of the human body and evaluate activity in the brain. A particular MRI method called magnetic resonance spectroscopy (MRS) can be used to study brain chemistry as well, which may help researchers who are studying new …

Accepts healthy volunteers
  • 106 views
  • 28 Oct, 2022
  • 1 location
Clarithromycin Mechanisms in Hypersomnia Syndromes

The purpose of this study is to evaluate a medication called clarithromycin for treating sleepiness in two related conditions, narcolepsy without cataplexy and idiopathic hypersomnia. Studies have shown that clarithromycin can reduce sleepiness, but researchers do not know how clarithromycin does this. This study will look at brain activity (on …

multiple sleep latency test
sleepiness
cataplexy
sleep disorders
clarithromycin
  • 306 views
  • 11 Jul, 2022
  • 1 location