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Found 54 clinical trials
Featured trial
A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Parallel-Group Study to Compare the Efficacy, Tolerability, and Safety of 3 Doses of Gabapentin Enacarbil (GSK1838262) With Placebo in the Treatment of Subjects With Moderate-to-Severe Primary Restless Legs Syndrome (RLS)

A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Parallel-Group Study to Compare the Efficacy, Tolerability, and Safety of 3 Doses of Gabapentin Enacarbil (GSK1838262) With Placebo in the

  • 626 views
  • 08 Nov, 2020
  • 1 location
National Adaptive Trial for PTSD Related Insomnia (NAP)

of this research study is to find out if taking medications called trazodone, eszopiclone, or gabapentin can help decrease symptoms of insomnia in patients with PTSD. PTSD is a form of intense

wake up
nightmares
gabapentin
trazodone
poor sleep
  • 715 views
  • 27 Jun, 2022
  • 34 locations
Gabapentin for Sleep in Critically Ill Patients

, and many pharmacologic solutions may actually increase the risk of adverse outcomes rather than impart benefits. Gabapentin, an anticonvulsant with applications in neuropathic pain, has been

  • 0 views
  • 17 Mar, 2022
  • 1 location
Gabapentin for Post-Operative Pain Control and Narcotic Reduction in Scrotal Surgery

The use of non-narcotic multi-modal analgesia to be used in the pre-operative, peri-operative and post-operative period to reduce or potentially eliminate narcotic usage following scrotal surgery. Research study results have shown that the use of anti-inflammatories in the peri-operative period reduces both pain and narcotic use. The hypothesis is that …

  • 0 views
  • 02 Oct, 2021
Short-term Effectiveness of Gabapentin Versus Placebo in Acute Lumbosacral Radiculalgia by Herniation Disc (GRADE) (GRADE)

The study consists in evaluating the analgesic efficacy of Gabapentin versus Placebo in the short term (72h) acute lumbosacral radiculalgia due to disc herniation. In addition to the

  • 0 views
  • 27 Apr, 2022
  • 3 locations
Comparing Pregabalin and Placebo in Patients With Persistent Globus Sensation (Lyrica)

To evaluate the relative merits, safety and effectiveness of pregabalin in globus patients compared with placebo.

  • 0 views
  • 21 Jul, 2022
  • 2 locations
A Comparative Study Between Analgesic Effect of Opioid Free and Opioid Based Anesthesia in Radical Nephrectomy Surgery

Patients undergoing nephrectomy have a high incidence of postoperative pain. In the perioperative period, these patients are often treated with patient-controlled opioids, epidural analgesia, or both. While effective, both of these treatment modalities carry risk, ie, opioids have a side effect profile including pruritus, nausea,vomiting, increase the risk of oversedation …

Accepts healthy volunteers
  • 0 views
  • 30 May, 2022
  • 1 location
Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough

This research study is evaluating the effectiveness of escalating doses of Amitriptyline and Duloxetine in reducing cough frequency in patients with refractory chronic cough (RCC)

  • 0 views
  • 11 Nov, 2021
  • 1 location
CBT-I Augmentation of TOP for Sobriety and Insomnia in AUD

Alcohol Use Disorder (AUD) and insomnia are more prevalent in Veterans than in the general community. Furthermore, insomnia is comorbid in 36-91% of individuals with AUD and jeopardizes recovery by increasing their risk for relapse and complicating their clinical profile. The VA/DoD guidelines recommend four medications for the treatment of …

  • 0 views
  • 19 Aug, 2021
  • 2 locations
Duloxetine for PHN

In this study, the investigators aim to investigate the preventive efficacy of prophylactic oral duloxetine during acute herpes zoster on postherpetic neuralgia and its safety.

  • 4 views
  • 02 Apr, 2021
  • 1 location