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Found 12 clinical trials
Micropulse for Suppression of Diabetic Macular Edema

Diabetic retinopathy is one of the most common complications of diabetes and diabetic macular edema (DME) is one of the most common causes of vision loss in diabetes. The purpose of this study is to determine if early intervention with micropulse laser treatment in eyes with good visual acuity (20/32 …

type 2 diabetes mellitus
retinopathy
diabetes
corrected visual acuity
blindness
  • 30 views
  • 01 May, 2021
  • 1 location
GOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)

fundus autofluorescence (FAF).

geographic atrophy
atrophy
fundus autofluorescence imaging
vaccination
age-related macular degeneration
  • 516 views
  • 19 Jul, 2021
  • 156 locations
Performance of Long-wavelength Autofluorescence Imaging

Fundus autofluorescence imaging has become an important diagnostic tool in ophthalmology, guiding diagnosis and assessment of progression of retinal diseases. This study investigates the

  • 0 views
  • 05 Aug, 2021
  • 1 location
Oral Metformin for Treatment of ABCA4 Retinopathy

> Participants will have fundus autofluorescence. A bright blue light will be shone into their eye. Participants will take metformin by mouth for 24 months. Participants will have study visits

  • 0 views
  • 27 Aug, 2021
  • 1 location
Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD

The purpose of this study is to determine whether metformin, an FDA-approved drug for the treatment of type II diabetes, is a safe and effective treatment to decrease the progression of geographic atrophy in non-diabetic patients with Age-related Macular Degeneration (AMD).

geographic atrophy
atrophy
drusen
age-related macular degeneration
mydriasis
  • 370 views
  • 11 May, 2021
  • 13 locations
Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

Background Age-related macular degeneration is a common eye disease in people over 50. The "dry" form of the disease can worsen into geographic atrophy, causing blind spots. Researchers want to learn if replacing older eye cells with younger ones can help treat this disease. Objective To test the safety of …

fluorescein angiography
fundus photography
visual impairment
angiography
geographic atrophy
  • 421 views
  • 22 Sep, 2021
  • 1 location
Retinal Displacement Rates in Pneumatic Retinopexy Versus Pars Plana Vitrectomy For Primary Retinal Detachment

Patients may experience metamorphopsia, or image distortion, after having vitrectomy to repair their rhegmatogenous retinal detachments (RRDs) especially those with a detached macula. Retinal displacement, as measured on autofluorescence photography, likely contributes to this distortion. There is no study in the scientific literature comparing the rate of retinal displacement and …

proliferative vitreoretinopathy
retinal tear
detached
retinopexy
vitrectomy
  • 5 views
  • 10 May, 2021
  • 1 location
Endophthalmitis Post Intravitreal Injections

Intravitreal injection (IVI) is an ophthalmological procedure used worldwide to treat ocular conditions. Its use has been steadily increasing for several years, because this method of drug delivery minimizes systemic exposure and allows for intraocular drug levels not achievable through systemic or topical drug administration. IVI of agents such as …

  • 0 views
  • 08 May, 2021
  • 1 location
Simultaneous OCT and B-FAF in Eyes With Alteration of the Foveal Contour

alterations may show an appearance, on blue fundus autofluorescence (B-FAF) imaging, reminiscent of lamellar macular hole. The aim of the study is to evaluate in detail these alterations recording

  • 0 views
  • 30 Jan, 2021
  • 1 location
Natural History Study of Usher Syndrome ( Light4Deaf )

Clinical centres in the LIGHT4DEAF consortium have developed and will continue to improve a reliable, early molecular diagnosis and protocols for full clinical characterisation of Usher syndrome, which will be valuable for the foreseen USH clinical trials. The clinical arm of the project aims at performing a deep-phenotyping of retinal …

  • 0 views
  • 27 Jan, 2021
  • 4 locations