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Found 273 clinical trials
Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas

Patients with glial brain tumors have increasingly improved outcomes, with median survival of 5-15 years. However, the treatments, including surgery, radiation, and chemotherapy, often lead to impaired attention, working memory, and other cognitive functions. These cognitive deficits frequently have significant impact on patient quality of life. Although currently, there is …

brain tumor
MRI Scan
karnofsky performance status
  • 25 Jan, 2021
  • 1 location
Dietary Fiber Effects on the Microbiome and Satiety

Strong evidence supports the association between high fiber (HiFi) diets (e.g. legumes, nuts, vegetables) and a reduced risk for chronic conditions such as cardiovascular disease (CVD), type 2 diabetes and some forms of cancer. However, the current U.S. average consumption of dietary fiber of 17g/day is significantly below the recommendation …

  • 16 Apr, 2021
  • 1 location
Impact of a Cognitive Intervention Enriched With Leisure Activities in Persons With Subjective Cognitive Decline

The team "Cognitive intervention, cognitive reserve and brain plasticity", Team 10, is part of the Canadian Consortium on Neurodegeneration in Aging (CCNA). The team's aim is to develop and test a multi-faceted intervention program meant to increase cognitive and brain reserve by providing cognitive stimulation through participation in cognitive training …

  • 05 Feb, 2021
  • 2 locations
Augmenting Cognitive Training In Older Adults

metabolic state. Functional magnetic resonance imaging (FMRI) will be used to assess brain response during working memory, attention, and memory encoding; the active cognitive abilities trained by CT

cognitive training
cognitive decline
  • 04 Mar, 2021
  • 3 locations
Venglustat in Combination With Cerezyme in Adult and Pediatric Patients With Gaucher Disease Type 3

GD3 patients by assessing: CSF Lyso-GL1 levels Modified Friedreichs Ataxia Rating Scale - Activities of Daily Living (FARS-ADL) Brain resting-state functional Magnetic

  • 13 Jun, 2021
  • 7 locations
Clinical Trial of Fluoxetine in Anxiety and Depression in Children and Associated Brain Changes

Objective: This protocol uses functional magnetic resonance imaging (fMRI) to examine neuro-cognitive correlates of pediatric and adult mood and anxiety disorders. The primary goal of the

mood disorder
major depressive disorder
depressive symptoms
  • 20 May, 2021
  • 1 location
Neurorehabilitation After Traumatic Brain Injury: Functional Magnetic Resonance Imaging Study

The current study aims to better understand cerebral plasticity mechanisms to optimize non-pharmacological rehabilitation approaches for patients with traumatic brain injury.

transcranial direct current stimulation
severe traumatic brain injury
cognitive rehabilitation
neurological rehabilitation
functional magnetic resonance imaging
  • 24 Jan, 2021
  • 1 location
Emotional Lived in Patients Suffering From Psychogenic Nonepileptic Seizures : Study by Functional Magnetic Resonance Imaging

Currently, hypothetical models of understanding Psychogenic Non-epileptic Seizures (PNES) involve emotional dysregulation. The hypothesis of a disorder of emotional experience is mainly based on behavioral data and disturbance of autonomic responses in response to images in emotional content (Mignot et al 2015, in submission; Bakvis et al 2013). Various imaging …

  • 22 Jun, 2021
  • 1 location
Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients

Persistent cough is a distressing symptom for people with respiratory disorders. Patients also often experience an ongoing urge-to-cough that prompts coughing, and which fails to resolve the sensation. Understanding how the brain controls cough and the urge-to-cough could lead to new cough suppressing therapies. The overall objective of this project …

  • 10 May, 2021
  • 1 location
Smell Exploration in Patients With Nasal Polyposis : Study by Functional Magnetic Resonance Imaging

functional Magnetic Resonance Imaging (fMRI). Brain activity will be measured by the intensity of brain signals and of the size of olfactory areas during olfactory stimulation before and after surgery. We

  • 26 Jan, 2021
  • 1 location