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Found 281 clinical trials
Perceptual Abnormalities and Their Malleability in BDD

A core symptom of body dysmorphic disorder (BDD) is perceptual distortions for appearance, which contributes to poor insight and delusionality, limits engagement in treatment, and puts individuals at risk for relapse. Results from this study will provide a comprehensive mechanistic model of brain, behavioral, and emotional contributors to abnormal perceptual …

Accepts healthy volunteers
obsessive-compulsive disorder
  • 0 views
  • 08 Jan, 2022
  • 2 locations
Project Health: Enhancing Effectiveness of a Dissonance-Based Obesity Prevention Program (PH)

This project seeks to improve the effectiveness of a novel dissonance-based obesity prevention program that has reduced future BMI gain and overweight/obesity onset by (a) experimentally testing whether implementing it in single- versus mixed-sex groups, which should increase dissonance-induction that contributes to weight gain prevention effects, and (b) experimentally testing …

Accepts healthy volunteers
  • 57 views
  • 15 Feb, 2022
  • 1 location
Sensorimotor Imaging for Brain-Computer Interfaces

The investigators will use fMRI to map movement activity in motor and somatosensory cortex using enriched imagery in people with chronic tetraplegia. The investigators expect that somatotopic organization of movement activity will be preserved in people with upper limb impairments, which can be quantified using the strength, area, and location …

  • 0 views
  • 05 May, 2022
  • 1 location
Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas

Patients with glial brain tumors have increasingly improved outcomes, with median survival of 5-15 years. However, the treatments, including surgery, radiation, and chemotherapy, often lead to impaired attention, working memory, and other cognitive functions. These cognitive deficits frequently have significant impact on patient quality of life. Although currently, there is …

brain tumor
stroke
seizure
karnofsky performance status
MRI Scan
  • 0 views
  • 23 Aug, 2021
  • 1 location
Questionnaire and Projective Color Association in Physiological Responses to Different Emotional Charge (PARC)

A sample of 101 individuals will be used for this purpose, where each of them will be exposed to 145 different stimuli. Comparison of their physiological responses to stimuli (cerebral blood flow, electrical activity of the brain, heart rate variability, and skin conductance response) and the perception of the stimuli …

Accepts healthy volunteers
  • 0 views
  • 06 Jun, 2022
  • 1 location
Dietary Fiber Effects on the Microbiome and Satiety

Strong evidence supports the association between high fiber (HiFi) diets (e.g. legumes, nuts, vegetables) and a reduced risk for chronic conditions such as cardiovascular disease (CVD), type 2 diabetes and some forms of cancer. However, the current U.S. average consumption of dietary fiber of 17g/day is significantly below the recommendation …

Accepts healthy volunteers
  • 0 views
  • 28 Oct, 2021
  • 1 location
Impact of a Cognitive Intervention Enriched With Leisure Activities in Persons With Subjective Cognitive Decline

The team "Cognitive intervention, cognitive reserve and brain plasticity", Team 10, is part of the Canadian Consortium on Neurodegeneration in Aging (CCNA). The team's aim is to develop and test a multi-faceted intervention program meant to increase cognitive and brain reserve by providing cognitive stimulation through participation in cognitive training …

  • 28 views
  • 05 Feb, 2021
  • 2 locations
Clinical Trial of Fluoxetine in Anxiety and Depression in Children, and Associated Brain Changes

Objective: This protocol uses functional magnetic resonance imaging (fMRI) to examine neuro-cognitive correlates of pediatric and adult mood and anxiety disorders. The primary goal of the

behavioral therapy
anxiety
social interaction
panic disorder
mood disorder
  • 721 views
  • 28 Jun, 2022
  • 1 location
Emotional Lived in Patients Suffering From Psychogenic Nonepileptic Seizures : Study by Functional Magnetic Resonance Imaging

Currently, hypothetical models of understanding Psychogenic Non-epileptic Seizures (PNES) involve emotional dysregulation. The hypothesis of a disorder of emotional experience is mainly based on behavioral data and disturbance of autonomic responses in response to images in emotional content (Mignot et al 2015, in submission; Bakvis et al 2013). Various imaging …

  • 1 views
  • 22 Jun, 2021
  • 1 location
Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome (IRM SAOS)

The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wakefulness. The …

apnea-hypopnea index
somnolence
Accepts healthy volunteers
obstructive sleep apnea
collapse
  • 0 views
  • 26 May, 2022
  • 1 location