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Found 273 clinical trials
Mapping Auricular Vagus Nerve Circuitry

This study will determine how vagus nerve stimulation affects human brain, stomach, and autonomic activity.

  • 24 Jan, 2021
A Preliminary Investigation of Pre-Frontal Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Cannabis Use Disorder

This investigation will preliminarily determine if a course of high frequency rTMS applied to the left dorsolateral prefrontal cortex, will reduce cue elicited craving, and cue reactivity in treatment seeking cannabis use disordered participants.

  • 19 Apr, 2021
  • 2 locations
Transcranial Magnetic Stimulation for Methadone Maintenance Therapy Combined With Methamphetamine Abuse

Repetitive transcranial magnetic stimulation (rTMS) has been used to treat opioid and methamphetamine addiction in previous studies, while no evidence was proved for patients methadone maintenance therapy with methamphetamine abuse. The aim of this study is to evaluating the effectiveness and safety of rTMS treatment for methamphetamine abuse in patients …

  • 27 Jan, 2021
  • 1 location
Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia

A stroke located in the left parieto-temporal junction is associated, in aphasic right-handed patients, with a poor prognosis for language recovery. The role of the right hemisphere in recovering post-stroke aphasia is still controversial. Our hypothesis, based on recent work in imaging, is that early activation of the right hemisphere …

  • 28 Jan, 2021
Effects of a Specific Substance in Smokers

Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may lead to the establishment of life-long smoking patterns. The goal of this project is to understand the …

  • 11 Mar, 2021
  • 1 location
The Causal Connection Between Sng and Muscle Acidosis

This proposed study suggests that peripheral tissue acidosis sensed by the somatosensory system (sngceptin) would evoke the sng perception in the brain. This hypothesis is based on investigators preliminary data that the peripheral muscle acidosis will evoked the central sng perception. This proposed study also identify the detection of brain …

  • 25 Jan, 2021
  • 1 location
Motor Imagery Intervention for Improving Gait and Cognition in the Elderly

The investigators propose a single-blind randomized clinical trial to determine if seniors show improved mobility (walking speed) and cognition following motor imagery (imagined walking) training. They hypothesize that imagined walking can be used as a rehabilitative tool for improving walking speed and cognition in the elderly, because it engages and …

  • 12 Apr, 2021
  • 1 location
Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction

A combination of oral vitamin A (VitA) and intense aromatic chemosensory smell training (ST) by pulse aromatic stimulation will expedite the neurosensory recovery of olfaction in patients suffering from prolonged COVID-19-related olfactory dysfunction (OD).

  • 31 May, 2021
  • 2 locations
Sensory Enrichment for Older Adults

This study evaluates the efficacy of multi-odorant enrichment on cognitive skills, olfactory function, and quality of life.

  • 21 Apr, 2021
  • 1 location
A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia

This study will test whether PF-06412562, a dopamine 1 partial agonist novel compound, affects working memory neural circuits in patients with early episode schizophrenia. The overall aim is to establish neuroimaging biomarkers of the Dopamine Receptor 1/Dopamine Receptor 5 Family (D1R/D5R) target engagement to accelerate development of D1R/D5R agonists in …

  • 03 Apr, 2021
  • 4 locations