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Found 273 clinical trials
Neural Circuit Biomarkers of Transcranial Magnetic Stimulation Study

The objective of this observational study is to test whether neuroimaging biomarkers of repetitive transcranial magnetic stimulation (TMS) can be prospectively replicated in a large ecologically valid sample. We focus on cognitive network connectivity as a predictive biomarker of the clinical effect of TMS, and as a response biomarker of …

  • 26 Jan, 2021
  • 1 location
Comparing Neural Responses to Food Images in EDNOS Patients and Healthy Controls Using fMRI

Currently, there is not a robust, testable neural model available that sufficiently explains the development and maintenance of anorexia nervosa (AN) a severe, often fatal, adolescent-onset eating disorder. Using state of the art neuroimaging and neuropsychological techniques, our objective is to identify neural mechanisms in the adolescent brain underlying AN. …

  • 08 May, 2021
  • 2 locations
Psychosocial Behavioral and Radiologic Changes Following Radiosurgery for Benign Neurologic Disease

A number of studies from the literature suggest important behavioral, psychosocial, or radiologic changes occur following significant neurologic events or interventions such as stroke, neurosurgery, medications, radiation, systemic therapy, or injury. The purpose of this study is to describe these changes with advanced neurologic imaging and targeted neurologic and neuropsychiatric …

  • 27 Jan, 2021
  • 1 location
Brain Computer Interface Complete locked-in State Communication

Electroencephalography (EEG) and/or near-infrared spectroscopy (NIRS) based Brain computer interface for communication in patients without any means of communication.

  • 22 Jan, 2021
  • 1 location
Detection and Characterization of Residual Masses in Lymphomas

The present study aims to further optimize a whole-body Diffusion-Weighted Magnetic Resonance Imagery (DW-MRI or DWI) protocol on 3 Tesla MR and/or new system combining 3Tesla MR and Positron Emission Tomography (PET), to develop and validate an automated whole-body parametric image analysis algorithm, and to determine the added value of …

diffuse large b-cell lymphoma
fludeoxyglucose f-18
follicular lymphoma
large b-cell lymphoma
  • 29 Jan, 2021
  • 2 locations
Striatal Connectivity and Clinical Outcome in Psychosis

This is an observational neuroimaging treatment study. This study involves examining the neural circuitry of controlled treatment of patients presenting with a first-episode of psychosis with risperidone or aripiprazole. Patients who present for treatment of a first psychotic episode with a schizophrenia spectrum diagnosis and who are eligible to undergo …

shared psychotic disorder
  • 26 Jan, 2021
  • 1 location
Social Integration During Psychiatric Inpatient Therapy as Predictor of Treatment Response

The present longitudinal study aims at (i) identifying neurobiological mechanisms associated with successful social integration during the treatment of inpatients with Borderline Personality Disorder (BPD) and (ii) improving biomarker-based predictions of treatment response by incorporating core metrics of social integration.

  • 06 Mar, 2021
  • 1 location
Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)

The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time (during the first year after the event), compared with a healthy control group. Brain …

  • 23 Jan, 2021
  • 1 location
Selective Attention in Alcohol Use Disorder

This study examines the selective attention to emotional- and alcohol- associated cues in alcohol- dependant and healthy participants.

  • 01 May, 2021
  • 1 location
Epigenetics and Protective Factors in the Preterm Infant

Preterm infants (PT) spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to unfavorable conditions with different effects on child development including long-term alterations in epigenetic regulation (DNA methylation). Recent studies document that these epigenetic changes are associated with behavioral modifications, such …

  • 27 Mar, 2021
  • 1 location