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Found 270 clinical trials
CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG (CONNECT-ME)

vegetative state. In order to circumvent the need for motor function, paradigms using functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) have been developed. According to a recent

acute brain injuries
vegetative state
coma
  • 4 views
  • 25 Feb, 2022
  • 1 location
Fatigue in Chronic Pain - Cognition, Emotional Aspects, Biomarkers, and Neuronal Correlates

22 healthy female controls using functional magnetic resonance imaging (fMRI) technology. During the fMRI examination, participants will also perform a 20-minute vigilance task in a scanner. Studies

Accepts healthy volunteers
chronic pain
anxiety
  • 0 views
  • 07 Oct, 2022
  • 1 location
(Epi)Genetic Modulators of Fear Extinction in Alcohol Dependence

functional magnetic resonance imaging (MRI) scan. Participants will lie on a table in a metal cylinder with a coil over their head. In the first scanning session, they will see pictures, do a simple task

anxiety
psychological stress
Accepts healthy volunteers
alcohol withdrawal syndrome
psychiatric disorder
  • 61 views
  • 23 Oct, 2022
  • 1 location
Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

dysfunction. Our preliminary data showed that pubertal adolescents with obesity and/or diabetes exhibit relative kidney hypoxia compared to normal weight controls using functional magnetic resonance imaging

dialysis
diabetes
glomerular filtration rate
Accepts healthy volunteers
insulin resistance
  • 0 views
  • 25 Mar, 2022
  • 1 location
Computational Psychiatric Approach for Prognosis of Medication-Resistant Depression

The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression. Subjects will be invited to be in this study because (1) they are a patient about to receive ECT treatment for depression, or (2) they are a patient diagnosed with …

Accepts healthy volunteers
depressive symptoms
depressed mood
  • 289 views
  • 28 Oct, 2022
  • 1 location
Cerebrovascular Reactivity and Oxygen Metabolism as Markers of Neurodegeneration After Traumatic Brain Injury

This grant award entitled, "Cerebrovascular Reactivity and Oxygen Metabolism as Markers for Neurodegeneration after Traumatic Brain Injury" (hereafter, "Neurovascular Study"), aims to determine if neurovascular contributors to neurodegeneration can serve as markers of the emergence or progression of degenerative processes after traumatic brain injury in middle-aged and older adults.

Accepts healthy volunteers
  • 0 views
  • 10 May, 2022
  • 1 location
Early Signs of Parkinson's Disease Pathology in the Colon of Patients With Irritable Bowel Syndrome

Bowel symptoms like constipation and abdominal pain are characteristic symptoms of irritable bowel syndrome (IBS). The pathogenesis and pathophysiology are not fully understood but subject to intense research, with emphasis on aberrations in the gut-brain axis, low-grade inflammation and gut barrier dysfunction that results in increased permeability and microbial translocation. …

Accepts healthy volunteers
alpha-synuclein
constipation
microbiota
abdominal pain
  • 0 views
  • 28 Oct, 2022
  • 1 location
The Impact of CBT on Shock-Potentiated Neural Circuity

This study will aim to test whether specific neural circuitry changes, proposed on the basis of a neurocognitive model of anxiety, are a mechanism of action for Cognitive Behavioural Therapy (CBT) interventions. This study aims to provide a theoretical model of the neurobiological mechanisms of CBT's therapeutic effect, where there …

  • 0 views
  • 22 Oct, 2022
  • 1 location
Stress and Brain Response Using MEG in PWS

Individuals with Prader-Willi Syndrome (PWS) have increased hunger and food seeking behaviour, as well as learning (cognitive) challenges. In addition, some patients with PW been shown to have low cortisol production, particularly in stressful situations. However, research examining how hormonal, cognitive, and psychological factors are interrelated PWS is limited. To …

Accepts healthy volunteers
hunger
  • 37 views
  • 07 Oct, 2022
  • 1 location
The Brain Metabolic Change in Chronic Cancer Pain Patient: FDG PET Image Study

Cancer pain deteriorated in quality of life and related with numerous psychosocial problems. Over the one third of cancer patient suffered from moderate to severe cancer pain, even under adequate pain management. The 18F-fluoro-2-deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) images can provide quantitative results in clinical oncology. As a …

fdg pet
chronic cancer pain
severe cancer
analgesia
positron emission tomography/computed tomography
  • 0 views
  • 17 Oct, 2022
  • 1 location