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Found 152 clinical trials
New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.

Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects. Frequently the first and only presentation is with an acute event (such as myocardial infarction or sudden cardiac deaths) during physical effort. Not only symptoms are often absent, but …

intravascular ultrasound
myocardial infarction
MRI
infarct
ischemia
  • 0 views
  • 23 Dec, 2021
  • 1 location
Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis (CHOICE-FR)

The purpose of the current study is to assess complete coronary physiology (FFR, RFR, CFR, IMR, and CT-FFR) in TAVI candidates with intermediate coronary artery stenosis before and 6 months after TAVI. This aims to determine how TAVI affects coronary blood flow and coronary microcirculatory function after longer-term follow-up, and …

  • 0 views
  • 06 May, 2022
  • 1 location
  • 1 views
  • 31 Jan, 2022
  • 1 location
ALDH Enzyme in CRF With Advanced GI Cancer (ALDHCRF)

primary endpoint is the change of FACIT-F (Functional Assessment of Chronic Illness Therapy-Fatigue) score on day 15 compared to baseline after chemotherapy. The secondary endpoint including change of

cancer
  • 0 views
  • 25 Mar, 2022
  • 1 location
Ischemia in Patients With Non-obstructive Disease (INOCA) in Italy INOCA IT Multicenter Registry" (INOCAIT)

-Cycle Ratio (RFR) of angiographic stenosis> 50%; In the presence of coronary angiographic stenosis <50% or> 50% but in the presence of a negative functional assessment (FFR> 0.80

heart disease
stenosis
ischemia
angiography
  • 0 views
  • 24 Mar, 2022
  • 1 location
Development of Novel Physiological CMR Methods in Health and Disease

functional assessment can now be done without breath-holds using advanced acceleration methods, allowing them to be used during exercise. A comprehensive understanding of functional-flow coupling at rest

heart disease
exercise stress test
Accepts healthy volunteers
  • 44 views
  • 02 Mar, 2022
  • 1 location
Postpartum Low-Dose Aspirin After Preeclampsia for Optimization of Cardiovascular Risk (PAPVASC) (PAPVASC)

. Treatment groups will receive 81 mg daily oral aspirin, while control groups will receive an equivalent placebo pill. Vascular functional assessment at study outset will take place, combining laser speckle

aspirin
  • 7 views
  • 01 May, 2022
  • 1 location
Evaluating the Feasibility of a Digital Health Coaching Program for Individuals Following CAR T Therapy

providers, and physical and psychosocial health following treatment. Health related quality of life (HRQoL) will be assessed with the Functional Assessment of Cancer Therapy-Lymphoma (FACT-L), health self

cancer
lymphoma
cell therapy
  • 0 views
  • 03 May, 2022
  • 1 location
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases

. Besides, the tolerability of hydroxytyrosol (HT) in MD patients will be evaluated. The primary outcome measure is the functional assessment of the patient's clinical outcomes by International

  • 0 views
  • 28 Jul, 2022
  • 1 location
Ultra-high-resolution CT vs. Conventional Angiography for Detecting Coronary Heart Disease

CHD as defined by coronary functional assessment. The primary end point will be the diagnostic accuracy by area-under-curve (AUC) method for identifying patients with hemodynamically significant CHD

heart disease
stenosis
myocardial infarction
computed tomography angiography
infarct
  • 2 views
  • 23 Jul, 2022
  • 1 location