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Found 153 clinical trials
Muscle Stimulation for Physical Function During Stem Cell Transplant

Some blood, bone marrow, and lymphatic (hematologic) cancers such as Hodgkin/Non-Hodgkin lymphomas, chronic lymphocytic leukemia, and multiple myeloma, are over-represented in Veterans due to exposures including Agent Orange and an increased percentage of patients of African American ethnicity. Hematologic transplantation (HCT) is a common treatment for these cancers, but often …

  • 14 May, 2022
  • 1 location
Effects of an Integrative Psychological Program in Bipolar Disorder

Bipolar disorder is related to a high level of personal, familial, social and economic burden. There is a need for feasible adjunctive psychological interventions to use in clinical practice as a complement of pharmacotherapy to enhance aspects that medication cannot reach. This project aims at develop and evaluate the impact …

psychiatric treatment
  • 22 Mar, 2022
  • 1 location
Fixed Versus Adjustable Loop in ACL Reconstruction

Study Aims and Objectives: To investigate the following null hypothesis: that there is no difference in clinical and functional outcome when comparing outcomes of Anterior Cruciate Ligament (ACL) reconstruction when comparing femoral side graft fixation with either a fixed versus an adjustable suspensory loop system. The research team will achieve …

knee joint laxity
meniscal tear
anterior cruciate ligament injury
  • 29 Jan, 2022
  • 1 location
Traditional Versus Alternative Alignment in TKR

As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients satisfied with their operation. Recently, attention has focussed on alignment of …

Accepts healthy volunteers
  • 30 May, 2022
  • 1 location
Understanding Factors That Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine Receptors

The goal of this proposal is to test the overall hypothesis that e-cigarettes (ECs) provide efficient nicotine delivery to the brain and arterial blood in non-EC-naïve smokers and e-cigarette users and that EC liquid characteristics modulate this effect. This study will test the hypothesis through complementary methods that include [ …

  • 23 Mar, 2022
  • 1 location
Functional Assessment by Virtual Online Reconstruction. The FAVOR III Europe Japan Study (FAVOR III EJ)

Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. QFR is estimated based on two angiographic projections. Studies have shown a good correlation with the present wire-based standard approach Fractional Flow Reserve (FFR) for assessment of intermediate coronary stenosis. The purpose of the …

chest pain
coronary artery stenosis
stable angina
  • 28 Jun, 2022
  • 37 locations
Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD) (PAL-LIVER)

> Primary Outcome: The change in quality of life from baseline to 3 months post enrollment as assessed by FACT-Hep (Functional Assessment of Cancer Therapy- Hepatobiliary). 14 Clinical

liver disease
functional assessment
  • 03 May, 2022
  • 18 locations
Identification of Neurocognitive Disorders by General Practitioners in Primary Care

, the cognitive status and the autonomy level in primary care. It relies on the clinical impression of the GP, a cognitive complaint interview for complaint and functional assessment thanks to the

  • 05 Jul, 2021
  • 1 location
An Open-Label Study to Assess the Anti-Tumor Activity and Safety of REGN1979, an Anti CD20 x Anti-CD3 Bispecific Antibody, in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (ELM-2)

health-related quality of life (HRQL), as measured by the validated instruments European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), Functional

follicular lymphoma
btk inhibitor
diffuse large b-cell lymphoma
alkylating agent
b-cell lymphoma
  • 20 Sep, 2022
  • 129 locations
BIZI ORAIN: Exercise for All People With Cancer

-), symptoms (Cancer-related fatigue - Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue), exposure to physical activity level objectively registered with Actigraph wGT3X-BT accelerometer

smoking cessation
cancer treatment
primary cancer
  • 12 Feb, 2022