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Found 9 clinical trials
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

vascular disease
mini-mental state examination
cancer
major neurocognitive disorder
neurodegenerative disorder
  • 178 views
  • 25 Feb, 2022
  • 1 location
Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 Pathology (Veri-T-001)

The purpose of the study is to test the safety and tolerability of twice daily Verdiperstat in patients with semantic variant primary progressive aphasia (svPPA) due to frontotemporal lobar

  • 0 views
  • 27 Apr, 2022
  • 1 location
Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Disease Using the PET Ligand PI-2620

The investigators will compare PI-2620 tau PET scans from patients with frontotemporal lobar degeneration (FTLD), patients with non-amnestic presentations of Alzheimer's disease (naAD), and

Accepts healthy volunteers
alzheimer's disease
  • 0 views
  • 24 Oct, 2022
  • 1 location
Treatment for Speech and Language in Primary Progressive Aphasia

Primary progressive aphasia (PPA) is a progressive neurological disorder that causes a gradual decline in communication ability as a result of selective neurodegeneration of speech and language networks in the brain. PPA is a devastating condition affecting adults as young as their 40's or 50's, depriving them of the ability …

Accepts healthy volunteers
mini-mental state examination
mental state examination
  • 0 views
  • 14 Apr, 2022
  • 2 locations
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents the formalized integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through

corticobasal degeneration
amyotrophic lateral sclerosis
progressive supranuclear palsy
dementia
dementia, frontotemporal
  • 236 views
  • 28 May, 2022
  • 23 locations
UPenn Observational Research Repository on Neurodegenerative Disease (UNICORN)

The aim of this study is to create a repository of both cross-sectional and longitudinal data, including cognitive, linguistic, imaging and biofluid biological specimens, for neurodegenerative disease research and treatment.

neurodegenerative disorder
amyotrophic lateral sclerosis
atrophy
progressive supranuclear palsy
dementia, frontotemporal
  • 2 views
  • 04 Oct, 2022
  • 1 location
Neurofilament Surveillance Project (NSP)

This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control

Accepts healthy volunteers
frontotemporal lobar degeneration
  • 12 views
  • 24 Mar, 2022
  • 7 locations
Metacognition in Semantic Dementia: Comparison With Alzheimer's Disease (META-DEM)

This study aims at exploring patients' ability to monitor their own memory performance depending on their primary deficit and the type of memory involved in the criterion task. The goal is to evaluate if semantic dementia (SD) and Alzheimer's disease (AD) differently affect patients' awareness of their memory abilities.

dementia
mini-mental state examination
Accepts healthy volunteers
alzheimer's disease
  • 0 views
  • 24 May, 2022
  • 6 locations
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Background Neurodegenerative disorders can lead to problems in movement or memory. Some can cause abnormal proteins to build up in brain cells. Researchers want to understand whether these diseases have related causes or risk factors. Objective To test people with movement or thinking and memory problems to see if they …

tau protein
abnormal protein
amyotrophic lateral sclerosis
aphasia
dementia
  • 61 views
  • 04 Oct, 2022
  • 1 location