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Found 66 clinical trials
Complication and Lung Function Impairment Prediction Using Perfusion and CT Air Trapping

The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection

lung carcinoma
ct scan
  • 0 views
  • 28 Mar, 2021
  • 1 location
The Role of Endothelium A and EGFR Receptor in Fibrocytes From Asthma With Obstructive Sleep Apnea

expression of epidermal growth factor receptor (EGFR), endothelin A receptor (ETAR) and connective tissue growth factor (CTGF) The association of those factors and annual decline of forced expiratory volume

EGFR
forced expiratory volume
  • 23 views
  • 23 Jan, 2021
  • 1 location
Daily Home Spirometry for Early Detection of Pulmonary Complications in Patients With COVID19

The aim of this preliminary study is to describe the potential decline in forced expiratory volume in 1 second (FEV1) or forced vital capacity (FVC) as measured by home spirometry in high-risk

respiratory symptom
organ failure
respiratory distress
pneumonia
dyspnea
  • 0 views
  • 13 Feb, 2021
  • 1 location
Evaluate the Therapeutic Effect of Inhaled Corticosteroid in Asthmatic Children

Inhaled corticosteroid (ICS) is considered the first line medication for asthma, however, the therapeutic effect is markedly different even in patients with almost similar clinical manifestations. Our study was designed to explore the clinical and genetic factors that may influence the effectiveness of ICS in asthmatic children.

corticosteroids
budesonide
  • 0 views
  • 25 Jan, 2021
  • 1 location
Sickle Cell Pro-Inflammatory Response to Interval Training Study

Recommendations for exercise prescription currently do not exist for individuals with sickle cell anemia (SCA) despite the known impact that SCA-related complications has on physical functioning and fitness. A major barrier to increasing physical activity in SCA is the concern that the well-described inflammatory effects of exercise could precipitate or …

thalassemia
asthma
electrophoresis
anemia
hemoglobin s
  • 8 views
  • 22 Jan, 2021
  • 3 locations
Early Rheumatoid Arthritis Lung Disease Study

The primary goal of this study is to investigate lung disease, through pulmonary function and high resolution chest CT, in newly diagnosed RA patients. Extra-articular disease occurs in approximately 50% of RA patients, with the lung being a common site of involvement. Investigators goal is to understand the prevalence of …

arthropathy
  • 5 views
  • 25 Jan, 2021
  • 1 location
Evaluation of Respiratory Function in Fibromyalgia

This study will evaluate respiratory function in people with fibromyalgia and whether or not breathing patterns in this patient group can be explained by stress, emotional or biomechanical variables. In addition, examine the relationship between physical ability and lactate values.

  • 0 views
  • 18 Jun, 2021
  • 2 locations
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)

RECOVER is a prospective, multicenter observational study designed to measure the real world clinical effectiveness of elexacaftor, tezacaftor and ivacaftor triple combination therapy (Kaftrio) in people with cystic fibrosis over a two year period. Measured outcomes include measures of lung function, lung inflammation, lung imaging, abdominal symptoms, gut inflammation, liver …

ivacaftor
elexacaftor
fibrosis
tezacaftor
  • 52 views
  • 23 Mar, 2021
  • 7 locations
Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers

Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco. The origin of this variability in susceptibility to develop COPD is unclear, but understanding its underlying biology has important implications for our ability to design suitable preventative and therapeutic strategies for …

  • 0 views
  • 15 May, 2021
  • 3 locations
An Integrative Genomic Approach to Solve tHe Puzzle of sevERe earLy-Onset COPD

Chronic Obstructive Pulmonary Disease (COPD) is characterized by a chronic airflow limitation associated with an abnormal inflammatory response of the airways to inhaled noxious particles or gases. It is the third leading cause of death worldwide, accounting for approximately 3 million deaths each year and the prevalence is predicted to …

obstruction
plethysmography
pulmonary function test
spirometry
lung volume reduction
  • 1 views
  • 23 Jan, 2021
  • 2 locations