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Found 76 clinical trials
Self-directed Versus Therapist-directed Re-loading on Incidence of Ulcer Recurrence

in this study will have diabetes and have a recently closed foot ulcer. About half will be specifically told how to return to walking and the other half will be told to return to walking slowly. How

plantar ulcers
foot ulcer
  • 02 Nov, 2021
  • 1 location
A Double-Blind, Randomized, Placebo-Controlled, Multicenter Clinical Study to Assess the Safety of DERMASEAL Advanced Wound Care Dressing for the Treatment of Chronic Non-healing, Neuropathic Diabetic Foot Ulcers

The goal of this clinical trial is to determine the safety of DERMASEAL for the treatment of non-healing, neuropathic diabetic foot ulcers. The main outcome measure is safety. A total of twenty

  • 23 Oct, 2022
  • 1 location
Short or Long Antibiotic Regimes in Orthopaedics (SOLARIO)

Research question: If adults with bone or joint infection have local antibiotic therapy, can they do without prolonged treatment with antibiotics by mouth (oral) or injection? Adults with bone or joint infections are usually given long courses of oral antibiotics or into a vein (intravenous) following surgery. It is also …

antibiotic therapy
localised pain
  • 23 Mar, 2022
  • 18 locations
Flexor Tenotomy and Ulcer Recurrence

The main purpose of this study is to assess the efficacy of flexor tenotomy on the prevention of recurrence of toe ulcers in people with diabetes and a history of toe ulceration. Additionally, the investigators aim to assess interphalangeal joints (IPJ) and metatarsophalangeal joint (MTPJ) angles in a weight-bearing and …

  • 22 Apr, 2022
  • 1 location
Comparison of Wound Healing Between MedCu Dressings With Copper Oxide and Negative Pressure Wound Therapy Treatment

Randomized multisite two arms study in which one arm of patients will be treated with Negative Pressure Wound Therapy (NPWT) known also as Vacuum-assisted closure (VAC) treatment ("VAC Arm") and the second arm of patients will be treated with MedCu wound dressings with copper oxide (COD) ("Copper Arm"). The study …

body mass index
hemoglobin a1c
negative pressure wound therapy
  • 12 Apr, 2023
  • 1 location
Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)

In participants with diabetic foot ulcers (DFUs), this study will assess complete wound closure by comparing synthetic hybrid-scale fiber matrix (Restrata®) with standard of care. In

  • 11 Apr, 2023
  • 3 locations
Closure Obtained With Vascularized Epithelial Regeneration for DFUs With SkinTE® (COVER DFUs)

The purpose of this study is to assess the safety and efficacy of SkinTE for treatment of Wagner grade 2 diabetic foot ulcers.

diabetic foot
treatment regimen
wound dressing
  • 22 Oct, 2022
  • 2 locations
A Clinical Investigation Comparing the Clinical Performance and Cost Effectiveness of Biatain® Silicone Compared With SoC (BISIL)

study will recruit in total 100 adult subjects with a venous leg ulcer or a diabetic foot ulcer no deeper than 2cm. Only ulcers with a duration of at least 8 weeks but no longer than a year will be

  • 05 Apr, 2023
  • 1 location
Multicentre Study on Diabetic Foot Treatment (MSDFT)

, investigators compared the therapeutic effects of these two methods on the healing of diabetes foot ulcers through a controlled clinical study.

  • 06 Apr, 2023
  • 1 location
Implementation of Telemedicine for Patient With Lower Extremity Wounds

The objective of this study is to determine if patients with lower extremity wounds in rural communities who undergo specialty referral through telemedicine have expedited care compared to patients who are treated through standard in person referral.

leg ulcer
  • 16 Mar, 2021
  • 1 location