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Found 69 clinical trials
A Study of Fluzoparib in Combination With mFOLFIRINOX in Patients With Resectable Pancreatic Cancer

The study is being conducted to: a) evaluate the tolerability and safety of the co-administration of Fluzoparib and FOLFIRINOX in patients with resectable pancreatic cancer, and establish a

  • 0 views
  • 27 Jan, 2021
  • 1 location
Sequential Use of AG and mFOLFIRINOX as Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer

The prognosis of pancreatic cancer is extremely poor. Current guidelines recommend Nab-paclitaxel, Gemcitabine and modified Folfirinox as the first-line chemotherapeutic regimen. Studies have

  • 3 views
  • 01 Feb, 2022
Chemotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

Compare the efficacy and tolerability of IRE in combination with either FOLFIRINOX or gemcitabine in patients with locally advanced pancreatic cancer.

folfirinox
pancreatic adenocarcinoma
adenocarcinoma
advanced pancreatic adenocarcinoma
gemcitabine
  • 17 views
  • 14 Feb, 2022
  • 1 location
Pancreatic Adenocarcinoma Signature Stratification for Treatment (PASS-01)

This is a randomized multicentre phase II trial with a large translational component. The trial will evaluate the two standard chemotherapy regimens: modified folfirinox (mFFX) and gemcitabine

  • 0 views
  • 02 May, 2022
  • 6 locations
mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma (SABER)

Modified FOLFIRINOX (mFOLFIRINOX) is the standard of care for patients with locally advanced pancreatic adenocarcinoma. While radiotherapy has been investigated for the management of resectable

  • 0 views
  • 25 Mar, 2022
  • 1 location
Brazilian Total Neoadjuvant Therapy Trial

a highly active chemotherapy called "FOLFIRINOX" during the 12 weeks between the end of radiation therapy and evaluation for surgery increases the rates of complete response and, therefore, allows

  • 0 views
  • 27 Oct, 2021
  • 1 location
Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer (CATARTIC)

emerged, in which systemic chemotherapy with fluorouracil and oxaliplatin (RAPIDO trial) or with the triplet FOLFIRINOX (as was used in the PRODIGE 23 study) is incorporated before or after the

capecitabine
fluorouracil
chemoradiotherapy
chemo-radiotherapy
adenocarcinoma
  • 0 views
  • 24 Mar, 2022
  • 1 location
Liposomal Irinotecan S-1 and Oxaliplatin in Advanced Pancreatic Adenocarcinoma

In present study, the investigators evaluate the safety and efficacy of OIS-derived NASOX regimen (nal-IRI, S-1, oxaliplatin) in advanced pancreatic cancer. NASOX regimen contains nal-IRI, which has recently been proven effective in pancreatic cancer.

pancreatic adenocarcinoma
drainage
adenocarcinoma
biliary obstruction
irinotecan
  • 0 views
  • 26 Jul, 2021
  • 2 locations
Resistance Training Intervention to Improve Physical Function in Patients With Pancreatic Cancer Receiving Combination Chemotherapy or Have Undergone Surgery PancStrength Study

This clinical trial studies the safety of a real-time tele-exercise resistance training (training done using a tablet) in maintaining skeletal muscle, strength, physical function, and health-related quality of life in patients with pancreatic cancer who are receiving combination chemotherapy or have undergone surgery for the treatment of pancreatic cancer. Tele-exercise …

  • 0 views
  • 17 Apr, 2021
  • 1 location
A Phase 2 Study of siG12D LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer (PROTACT)

In this Phase II study a dose of 2.8 mg (eight 0.35 mg siG12D-LODERs) will be administered in 12-week cycles to patients with unresectable or borderline resectable locally advanced pancreatic cancer combined with chemotherapy treatment. Primary Outcome: ORR at 6 months.

folfirinox
adenocarcinoma
paclitaxel
measurable disease
cancer chemotherapy
  • 100 views
  • 01 Mar, 2022
  • 6 locations