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Found 69 clinical trials
FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma

(FOLFIRINOX). Main objective of the study is median overall survival.

gastric adenocarcinoma
docetaxel
absolute neutrophil count
combinations
leucovorin
  • 9 views
  • 22 Apr, 2021
  • 1 location
Combination of Anti-PD-1 Antibody and Chemotherapy in Pancreatic Cancer

The prognosis of pancreatic cancer is extremely poor. Current guidelines recommend FOLFIRINOX or modified-FOLFIRINOX as the first-line chemotherapeutic regimen. Studies have shown that

cancer chemotherapy
breast ductal carcinoma
folfirinox
neutrophil count
monoclonal antibodies
  • 32 views
  • 09 Feb, 2022
  • 1 location
Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 is Administered in Combination With IV Modified FOLFIRINOX (mFFX) With or Without IV Budigalimab Compared to mFFX in Adult Participants With Untreated Pancreatic Cancer Metastasis

in participants 18 to 75 years of age with a body weight greater than or equal to 35 kg with Metastatic Pancreatic Cancer Disease treated with Intravenous (IV) infusion of modified FOLFIRINOX (mFFX

metastatic pancreatic cancer
folfirinox
measurable disease
adenocarcinoma
pancreatic adenocarcinoma
  • 2 views
  • 04 Jun, 2022
  • 15 locations
Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer (NORAD01)

This study is a non-inferiority phase III randomised trial comparing preoperative chemotherapy alone (modified FOLFIRINOX) to chemotherapy followed by chemoradiotherapy in patients with primary

chemoradiotherapy
oxaliplatin
capecitabine
irinotecan
carcinoma
  • 0 views
  • 01 Jul, 2022
  • 3 locations
FOLFIRINOX + 9-Ing-41 + Losartan In Pancreatic Cancer

of the study drugs involved in this study are: 9-ING-41 Losartan Ferumoxytol FOLFIRINOX (made up of 4 different drugs): 5-Fluorouracil (5-FU

  • 0 views
  • 17 Jun, 2022
  • 1 location
FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer

(FOLFIRINOX) in patients with resectable pancreatic cancer.

cancer chemotherapy
oxaliplatin
folfirinox
irinotecan
metastasis
  • 2 views
  • 27 Apr, 2022
  • 1 location
Neoadjuvant FOLFIRINOX in the Treatment of Locally Advanced Gastric Cancer

Phase II single-arm study designed to evaluate the efficacy and safety of preoperative chemotherapy with FOLFIRINOX regimen. The investigators will include 27 patients with resectable locally

  • 0 views
  • 27 Jan, 2021
  • 1 location
Concurrent FOLFIRINOX Plus High Intensity Focused Ultrasound for Pancreatic Cancer

In patients diagnosed with locally advanced pancreatic cancer (LAPC)/borderline resectable pancreatic cancer (BRPC) and planned chemotherapy using FOLFIRINOX, high intensity focused ultrasound

  • 0 views
  • 08 Mar, 2022
  • 1 location
CEND-1 in Combination With Neoadjuvant FOLFIRINOX With or Without Panitumumab

This is a phase IB/IIA trial to ensure the safety of CEND-1 in combination with with Folfirinox with or without Panitumumab for treatment of pancreatic, colon and appendiceal cancers

cancer chemotherapy
breast ductal carcinoma
fluorouracil
oxaliplatin
folfirinox
  • 0 views
  • 01 Dec, 2021
  • 3 locations
Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

This is a research study to evaluate how the genetic makeup of Pancreatic Ductal Adenocarcinoma (PDAC) can affect the response to FDA-approved chemotherapy treatment, FOLFIRINOX, given before

ductal adenocarcinoma
leucovorin
pdac
metastatic pancreatic cancer
fluorouracil
  • 10 views
  • 15 Jun, 2022
  • 1 location