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Found 73 clinical trials
A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer

with the modified FOLFIRINOX regimen alone; and the irreversible electroporation (IRE) arm, receiving chemotherapy with the modified FOLFIRINOX regimen followed by IRE with the NanoKnife System using

adenocarcinoma
pancreatic adenocarcinoma
folfirinox
  • 1 views
  • 27 Jul, 2020
  • 8 locations
Trial of Infusional FOLFIRINOX in First Line Treatment of Advanced Biliary Tract Cancers

This study is to evaluate the response rate and toxicity profile of infusional 5 fluorouracil, leucovorin, oxaliplatin and irinotecan (FOLFIRINOX) in first-line treatment of advanced biliary

leucovorin
biliary cancer
fluorouracil
irinotecan
renal function
  • 5 views
  • 08 Nov, 2020
  • 1 location
Comparison FOLFIRINOX Panitumumab vs mFOLFOX6 Panitumumab in RAS/B-RAF Wild-type Metastatic Colorectal Cancer Patients

National trial, multicenter, randomized, phase II assessing FOLFIRINOX + Panitumumab versus mFOLFOX6 + Panitumumab in metastatic colorectal cancer patients selected by RAS and B-RAF status from

leucovorin
fluorouracil
irinotecan
neutrophil count
adenocarcinoma
  • 15 views
  • 02 Jul, 2020
  • 9 locations
A Study of Administering FOLFIRINOX Before Surgery For Potentially Curable Pancreatic Cancer

surgery can improve the overall survival in patents with localized pancreatic cancer. One of these chemotherapy regimen is combination of fluorouracil, oxaliplatin, irinotecan, leucovorin (FOLFIRINOX

pancreatic adenocarcinoma
leucovorin
fluorouracil
diabetes
irinotecan
  • 20 views
  • 08 Nov, 2020
  • 1 location
FOLFOX vs Gemcitabine in Patients With Metastatic Pancreatic Cancer Non-fit to FOLFIRINOX

this disease remains very poor with an overall 5-year survival rate less than 5%. The FOLFIRINOX regimen (5-fluorouracil [5-FU], folinic acid, irinotecan, and oxaliplatin) and the combination

metastatic pancreatic cancer
leucovorin
immunomodulators
fluorouracil
irinotecan
  • 0 views
  • 23 Aug, 2020
Gemcitabine and Paclitaxel vs Gemcitabine Alone After FOLFIRINOX Failure in Metastatic Pancreatic Ductal Adenocarcinoma

Ductal Adenocarcinoma (PDAC) after FOLFIRINOX failure or intolerance.

pdac
serum pregnancy test
paclitaxel
pancreatic ductal adenocarcinoma
folfirinox
  • 0 views
  • 31 Aug, 2020
  • 23 locations
Safety Tolerability and Efficacy of Regorafenib in Combination With FOLFIRINOX in Patients With Colorectal Cancer

Safety, tolerability and efficacy of regorafenib in combination with FOLFIRINOX in patients with RAS-mutated metastatic colorectal cancer: a dose-escalation, phase I/II trial

thromboplastin
regorafenib
lipase
international normalized ratio
hysterectomy
  • 1 views
  • 14 Jun, 2020
  • 1 location
Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer

The prognosis of pancreatic cancer is extremely poor. NCCN guidelines recommend FOLFIRINOX or modified-FOLFIRINOX as the first-line chemotherapeutic regimen. Studies have shown that

pdac
metastasis
metastatic pancreatic cancer
folfirinox
  • 11 views
  • 15 Dec, 2019
  • 1 location
Disulfiram-Copper Gluconate in Met Pancreas Cancer w Rising CA19-9 on Abraxane-Gemzar FOLFIRINOX or Gemcitabine

) plus gemcitabine (Gemzar) or FOLFIRINOX or single-agent gemcitabine (Gemzar). Patient must have received a minimum of 8 weeks of treatment and have rising CA-19-9 levels in the absence of radiographic

pancreatic adenocarcinoma
neutrophil count
adenocarcinoma
gemcitabine
ct scan
  • 1 views
  • 15 Dec, 2019
  • 1 location
Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

The purpose of this study is to evaluate the efficacy of modified FOLFIRINOX followed by stereotactic body radiotherapy (SBRT) in patients with borderline resectable pancreatic cancer (BRPC) and

resectable pancreatic cancer
carcinoma
pancreatic adenocarcinoma
stereotactic body radiation therapy
fluorouracil
  • 3 views
  • 22 Dec, 2019