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Found 21 clinical trials
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A Study of the Prevalence of Apolipoprotein L1 (APOL1) Alleles Among Individuals With Proteinuric Kidney Disease Who Are of Recent African Ancestry or Geographic Origin

A Study of the Prevalence of Apolipoprotein L1 (APOL1) Alleles Among Individuals With Proteinuric Kidney Disease

diabetes
  • 0 views
  • 29 Jul, 2021
  • 1 location
None
A Study to Evaluate PF-06730512 in Adults With Focal Segmental Glomerulosclerosis (FSGS)

FSGS.

tubulointerstitial fibrosis
glomerular filtration rate
focal segmental glomerulosclerosis
total protein
immunosuppressive agents
  • 226 views
  • 14 Aug, 2021
  • 107 locations
None
Atrasentan in Patients With Proteinuric Glomerular Diseases

The AFFINITY Study is a phase 2, open-label, basket study to evaluate the efficacy and safety of atrasentan in patients with proteinuric glomerular disease who are at risk of progressive loss of renal function.

ras inhibitor
nephropathy
atrasentan
total protein
renal function
  • 0 views
  • 12 Sep, 2021
  • 26 locations
None
PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

This is a phase III, multicenter, randomized, open label, clinical trial to test that hypothesis that plasmapheresis plus rituximab prior to kidney transplantation can prevent recurrent FSGS in

kidney transplant
rituximab
primary focal segmental glomerulosclerosis
obesity
investigational drug
  • 83 views
  • 15 Sep, 2021
  • 1 location
None
Use of Acthar in Patients With FSGS That Will be Undergoing Renal Transplantation

This study will evaluate the use of Acthar in patients to undergo renal transplantation and will measure the rate of FSGS recurrence.

kidney transplant
acthar
  • 33 views
  • 27 Jan, 2021
  • 1 location
None
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

segmental glomerulosclerosis (FSGS) in Japan and referred in the Guidelines for the Treatment of Nephrotic Syndrome endorsed by The Japanese Society of Nephrology. This study is conducted as a post

kidney transplant
primary focal segmental glomerulosclerosis
nephrotic syndrome
alternative therapies
focal segmental glomerulosclerosis
  • 36 views
  • 07 May, 2021
  • 8 locations
None
Post Approval Study for Treatment of Drug-resistant Adult Primary FSGS Using the LIPOSORBER LA-15 System

associated with primary focal segmental glomerulosclerosis, when the standard treatment options, including corticosteroid and/or calcineurin inhibitors treatments, have been unsuccessful or not well

kidney transplant
glomerular filtration rate
primary focal segmental glomerulosclerosis
nephrotic syndrome
focal segmental glomerulosclerosis
  • 14 views
  • 05 May, 2021
  • 10 locations
None
Tumor Necrosis Factor Inhibition in Focal Segmental Glomerulosclerosis and Treatment Resistant Minimal Change Disease

develop individualized treatment options for future patients with TNF driven Focal segmental glomerulosclerosis (FSGS) or minimal change disease (MCD).

angiotensin
angiotensin-converting enzyme
kidney biopsy
biopsy tissue
total protein
  • 12 views
  • 11 Aug, 2021
  • 4 locations
None
Efficacy of Rituximab in Comparison to Continued Corticosteroid Treatment in Idiopathic Nephrotic Syndrome

change disease or focal segmental glomerulosclerosis unresponsive to 8 weeks of high dose prednisone . patients either receive 2 doses of Rituximab 375 mg/m2 iv at time 0 and 14 days with

rituximab
prednisone
total protein
minimal change disease
prednisone 1 mg
  • 52 views
  • 22 Jan, 2021
  • 1 location
None
A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy Focal Segmental Glomerulosclerosis and Treatment-Resistant Minimal Change Disease

This is a phase 2a study evaluating the safety and tolerability of multiple ascending doses of GFB-887 in patients with diabetic nephropathy (DN), focal segmental glomerulosclerosis (FSGS), and

angiotensin
angiotensin-converting enzyme
segmental glomerulosclerosis
glycated hemoglobin
hemoglobin a1c
  • 69 views
  • 30 Sep, 2021
  • 57 locations