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Found 12 clinical trials
Midodrine and Fludrocortisone for Vasovagal Syncope

controversy about the efficacy of midodrine and fludrocortisone as adjunct pharmacological interventions for the prevention of VVS. In the COMFORTS trial, we are going to evaluate the efficacy of midodrine

  • 4 views
  • 25 Apr, 2021
  • 1 location
Hydrocortisone and Fludrocortisone for Critical Illness-related Corticosteroid Insufficiency (HORNbILL)

The study aims at assessing the efficacy and the safety of hydrocortisone combined with fludrocortisone compared to placebo in ICU adults with critical illness related corticosteroid

  • 0 views
  • 21 Mar, 2022
Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock. (COCCA)

The purpose of this randomized controlled trial is to evaluate the hemodynamic effect of low dose corticosteroid therapy (hydrocortisone and fludrocortisone) in the treatment of adult

congestion
hypoperfusion
ejection fraction
oliguria
pulmonary artery occlusion
  • 24 views
  • 30 Jun, 2022
  • 14 locations
Efficacy and Tolerance of Flucortac in Patients With Orthostatic Neurogenic Hypotension

To evaluate the efficacy of a 4-week fludrocortisone (FLU) treatment on systolic blood pressure depression after 5 minutes of active orthostatism in patients with neurogenic orthostatic

  • 0 views
  • 02 Sep, 2021
  • 1 location
A Randomized, Prospective, Placebo-Controlled, Crossover Study of Atomoxetine in the Prevention of Vasovagal Syncope (POST7) (POST7)

and not surprisingly with clinical anxiety. Although conservative measures help many patients there remain many who require more care. CIHR-funded studies have shown that fludrocortisone and midodrine

  • 13 views
  • 24 Oct, 2022
  • 1 location
Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis (RECORDS)

Main objective and primary endpoint: To compare the effect hydrocortisone plus fludrocortisone vs. placebo on a composite of death or persistent organ dysfunction - defined as continued

FIO2
lactate level
pneumonia
shock
epinephrine
  • 0 views
  • 23 May, 2022
  • 1 location
Fludrocortisone Dose Response Relationship in Septic Shock - FluDReSS

The purpose of this study is to determine the most suitable dose of Fludrocortisone in reversal of sepsis and shock associated with sepsis in patients who are admitted to the ICU. The

  • 0 views
  • 10 Apr, 2021
  • 9 locations
Stress & Social Cognition in BPD (Part 2) (SOKO-2)

The investigators will examine how a combination of pharmacological mineralocorticoid receptor (MR) stimulation and psychosocial stress will influence prosocial behavior in patients with Borderline Personality Disorder (BPD) compared to healthy controls (HC).

body mass index
Accepts healthy volunteers
  • 0 views
  • 30 Apr, 2022
  • 1 location
Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients …

orthostatic hypotension
hypertension
cpap
  • 3 views
  • 04 Oct, 2022
  • 1 location
Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

The purpose of this study is to learn more about the effects of abdominal compression and the medication midodrine, two interventions used for the treatment of orthostatic hypotension (low blood pressure on standing), on hemodynamic markers of cardiovascular risk. The study will be conducted at the Vanderbilt University Medical Center …

systolic blood pressure
orthostatic hypotension
midodrine
pure autonomic failure
  • 0 views
  • 19 Jun, 2022
  • 1 location