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Found 274 clinical trials
MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis

busulfan- and fludarabine-based conditioning regimens with busulfan therapeutic drug monitoring (TDM) for patients with various inherited metabolic disorders (IMD) and severe osteopetrosis (OP).

peroxisomal disorder
treatment regimen
preparative regimen
fludarabine
leukodystrophy
  • 137 views
  • 25 Jan, 2021
  • 1 location
Transplantation Using Reduced Intensity Approach for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow

-matched related donors. Preparation before transplant includes the chemotherapy drugs hydroxyurea, fludarabine, thiotepa, anti-thymocyte globulin, and cyclophosphamide. It also includes radiation.

anti-thymocyte globulin
chest syndrome
preparative regimen
fludarabine
hemoglobin s
  • 33 views
  • 13 Feb, 2021
  • 1 location
  • 31 views
  • 24 Jan, 2021
  • 7 locations
Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

This is a single arm, phase II trial of HLA-haploidentical related hematopoietic cells transplant (Haplo-HCT) using reduced intensity conditioning (fludarabine and melphalan and total body

total body irradiation
autologous transplantation
t-cell lymphoma
myeloid leukemia
melphalan
  • 5 views
  • 11 Mar, 2021
  • 1 location
Human BCMA Targeted T Cells Injection Therapy for BCMA-positive Relapsed/Refractory Multiple Myeloma

chemotherapy regimen of fludarabine and cyclophosphamide followed by a single infusion of BCMA CAR+ T cells.

  • 0 views
  • 11 Mar, 2021
  • 3 locations
Safety and Efficacy of ALLO-316 in Subjects With Advanced or Metastatic Clear Cell Renal Cell Carcinoma

or metastatic clear cell renal cell carcinoma after a lymphodepletion regimen comprising fludarabine, cyclophosphamide, and ALLO-647 to define a Phase 2 dose.

  • 0 views
  • 08 Apr, 2021
  • 2 locations
Risk Stratification Directed Conditioning Regimen for Haploidentical HSCT in SAA

acquired SAA.But some patients with high risk factors may not tolerate CTX 200mg/kg,alternative conditioning regimen including Bu/Fludarabine/dercreased CTX was studied in this trial.

aplastic anemia
severe aplastic anemia
cyclophosphamide
fludarabine
conditioning regimen
  • 0 views
  • 23 Jan, 2021
  • 1 location
JSP191 Antibody Targeting Conditioning in MDS/AML Patients Undergoing Hematopoietic Cell Transplantation

This is a Phase 1 study to evaluate the safety and tolerability of an antibody conditioning regimen known as JSP191, in combination with low dose radiation and fludarabine, in patients with

  • 0 views
  • 27 Jan, 2021
  • 6 locations
Giving Chemotherapy for a Shortened Amount of Time Before a Stem Cell Transplantation

The purpose of this study is to see if a condensed version of the chemotherapy regimen busulfan, melphalan, fludarabine (bu/mel/flu) and the drug antithymocyte globulin (ATG-also referred to as

blast crisis
acute leukemia
fludarabine
melphalan
myeloid leukemia
  • 5 views
  • 27 Jan, 2021
  • 1 location
  • 0 views
  • 24 Jan, 2021
  • 3 locations