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Found 279 clinical trials
Venetoclax and Sequential Busulfan Cladribine and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

This randomized phase II trial studies how well venetoclax and sequential busulfan, cladribine, and fludarabine phosphate before donor stem cell transplant work in treating patients with acute

remission
ejection fraction
bone marrow procedure
direct bilirubin
white blood cell count
  • 13 views
  • 15 Feb, 2021
  • 1 location
Intensity Modulated Total Marrow Irradiation Fludarabine Phosphate and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

This phase I trial studies the side effects and the best dose of intensity modulated total marrow irradiation (IMTMI) when given together with fludarabine phosphate and melphalan in treating

hematologic malignancy
melphalan
stem cell transplantation
white blood cell count
myeloid leukemia
  • 13 views
  • 27 Jan, 2021
  • 1 location
Propylene Glycol-Free Melphalan HCl (EVOMELA ) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

This is an open-label, single-arm, phase II study to determine the safety of propylene glycol-free melphalan HCl (EVOMELA), in combination with fludarabine and total-body irradiation-based

myeloablative conditioning
hematologic malignancy
melphalan
karnofsky performance status
ejection fraction
  • 7 views
  • 24 Jan, 2021
  • 1 location
Induction of Mixed Hemopoietic Chimerism in Patients Using Fludarabine Low Dose TBI PBSC Infusion and Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil

Induction of mixed hemopoietic chimerism in patients using Fludarabine, Low Dose TBI, PBSC Infusion and post transplant in immunosuppression w/CSA & Mycophenolate Mofetil

  • 14 views
  • 07 Nov, 2020
  • 1 location
Fludarabine Phosphate Cytarabine Filgrastim-sndz Gemtuzumab Ozogamicin and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

This phase II trial studies the side effects and how well fludarabine phosphate, cytarabine, filgrastim-sndz, gemtuzumab ozogamicin, and idarubicin hydrochloride work in treating patients with

monoclonal antibodies
remission
ejection fraction
colony-stimulating factors
leukemia
  • 24 views
  • 08 Apr, 2021
  • 1 location
Feasibility and Efficacy Study of Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation (HCT) With Fludarabine Busulfan and Total Body Irradiation (TBI)

The purpose of this study is to evaluate the OS, RFS, and TRM after HCT with low-dose total body irradiation, fludarabine, and busulfan conditioning.

cell transplantation
busulfan
transplant conditioning
fludarabine
total body irradiation
  • 36 views
  • 07 Nov, 2020
  • 1 location
Total Marrow and Lymphoid Irradiation Fludarabine and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

This phase I studies the side effects and best dose of total marrow and lymphoid irradiation when given together with fludarabine and melphalan before donor stem cell transplant in treating

white blood cells
stem cell transplantation
ejection fraction
bone marrow procedure
hla-a
  • 17 views
  • 19 Feb, 2021
  • 1 location
MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian Fallopian Tube or Primary Peritoneal Cancer

Phase I study to establish safety and feasibility of intraperitoneally administered lentiviral transduced MOv19-BBz CAR T cells with or without cyclophosphamide + fludarabine as lymphodepleting

neutrophil count
cancer chemotherapy
chemotherapy regimen
peritoneal carcinoma
peritoneal cancer
  • 32 views
  • 12 Feb, 2021
  • 1 location
Epigenetic Reprogramming in Relapse/Refractory AML

This is a pilot study using decitabine and vorinostat before and during chemotherapy with fludarabine, cytarabine and G-CSF (FLAG).

blast cells
remission
ejection fraction
direct bilirubin
residual tumor
  • 182 views
  • 25 Jan, 2021
  • 34 locations
Flu-Bu-Mel Conditioning Regimen for Myeloid Disease

For patients with acute myeloid leukemia (AML) or myelodyspasia syndrome undergoing allo-HSCT, the conditioning regimen will be 5-day Fludarabine, 2-day Busulifan and 2-day melphalan

  • 0 views
  • 26 Jan, 2021
  • 2 locations