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Found 268 clinical trials
Induction of Mixed Hemopoietic Chimerism in Patients Using Fludarabine Low Dose TBI PBSC Infusion and Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil

Induction of mixed hemopoietic chimerism in patients using Fludarabine, Low Dose TBI, PBSC Infusion and post transplant in immunosuppression w/CSA & Mycophenolate Mofetil

  • 14 views
  • 07 Nov, 2020
  • 1 location
Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes

The study is a Phase II clinical trial. Patients will receive intensity modulated total marrow irradiation (TMI) at a dose of 9 Gy with standard myeloablative fludarabine/ i.v. targeted busulfan

refractory acute myeloid leukemia (aml)
busulfan
remission
myelodysplastic syndromes
blast cells
  • 6 views
  • 11 Jun, 2021
  • 1 location
Venetoclax and Sequential Busulfan Cladribine and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

This randomized phase II trial studies how well venetoclax and sequential busulfan, cladribine, and fludarabine phosphate before donor stem cell transplant work in treating patients with acute

remission
human chorionic gonadotropin
fludarabine
bone marrow procedure
cell transplantation
  • 13 views
  • 15 Feb, 2021
  • 1 location
Intensity Modulated Total Marrow Irradiation Fludarabine Phosphate and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

This phase I trial studies the side effects and the best dose of intensity modulated total marrow irradiation (IMTMI) when given together with fludarabine phosphate and melphalan in treating

bone marrow transplant
allogeneic bone marrow transplantation
hematologic malignancy
carbon monoxide
myeloid leukemia
  • 13 views
  • 27 Jan, 2021
  • 1 location
Propylene Glycol-Free Melphalan HCl (EVOMELA ) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

This is an open-label, single-arm, phase II study to determine the safety of propylene glycol-free melphalan HCl (EVOMELA), in combination with fludarabine and total-body irradiation-based

myeloablative conditioning
fungal infection
carbon monoxide
renal function
karnofsky performance status
  • 7 views
  • 02 Jun, 2021
  • 1 location
Total Marrow and Lymphoid Irradiation Fludarabine and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

This phase I studies the side effects and best dose of total marrow and lymphoid irradiation when given together with fludarabine and melphalan before donor stem cell transplant in treating

hydroxyurea
chromosome abnormality
serum bilirubin level
chromosomal abnormalities
fludarabine
  • 17 views
  • 19 Feb, 2021
  • 1 location
MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian Fallopian Tube or Primary Peritoneal Cancer

Phase I study to establish safety and feasibility of intraperitoneally administered lentiviral transduced MOv19-BBz CAR T cells with or without cyclophosphamide + fludarabine as lymphodepleting

cns metastases
peritoneal cancer
metastasis
tumor cells
cyclophosphamide
  • 32 views
  • 12 Feb, 2021
  • 1 location
  • 0 views
  • 27 Jan, 2021
  • 5 locations
  • 0 views
  • 01 May, 2021
  • 3 locations
Aza-Ven Followed by Reduced Toxicity Conditioning Regimen (MBF) as Salvage Therapy for Refractory AML.

of Fludarabine + Busulfan + Melphalan as salvage treatment in patients with refractory AML .

  • 0 views
  • 09 Jun, 2021
  • 3 locations