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Found 268 clinical trials
Donor Stem Cell Transplant With Treosulfan Fludarabine and Thiotepa in Treating Patients With Non-malignant Disorders

This phase II trial studies how well donor stem cell transplant, treosulfan, fludarabine, and thiotepa work in treating patients with non-cancerous disorders. Giving chemotherapy before a donor

primary cancer
bone marrow procedure
  • 0 views
  • 20 May, 2021
  • 2 locations
Fludarabine in Combination With Daunorubicin and Cytarabine Liposome in Newly-diagnosed Acute Myeloid Leukemia.

This phase 2 clinical trial will evaluate the effectiveness and safety of fludarabine in combination with CPX-351 in patients with untreated AML. Patients will receive fludarabine and CPX-351

  • 0 views
  • 08 Apr, 2021
  • 1 location
Study of Fludarabine With Pegylated Liposomal Doxorubicin Versus Pegylated Liposomal Doxorubicin Alone In Patients With Platinum Resistant/Refractory Ovarian Cancer

The purpose of the study is to evaluate the efficacy and toxicity of fludarabine with pegylated liposomal doxorubicin versus pegylated liposomal doxorubicin alone in patients with platinum

ovarian epithelial carcinoma
doxorubicin
cancer chemotherapy
carcinoma
neutrophil count
  • 4 views
  • 21 Jan, 2021
  • 1 location
Sorafenib Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

This phase I/II trial studies the best dose of sorafenib when given together with busulfan and fludarabine in treating patients with acute myeloid leukemia that has come back or does not respond

cell transplantation
fludarabine
tacrolimus
busulfan
cyclophosphamide
  • 13 views
  • 23 Jan, 2021
  • 2 locations
Fludarabine Phosphate Cyclophosphamide Total Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

This phase II trial studies how well fludarabine phosphate, cyclophosphamide, total body irradiation, and donor stem cell transplant work in treating patients with blood cancer. Drugs used in

cytotoxic therapy
blood stem cell transplant
b cell lymphoma
conditioning regimen
hemoglobinopathy
  • 134 views
  • 24 Jan, 2021
  • 1 location
Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer

Primary Objective: The primary objective of the study is to evaluate the safety of repeat administration of a dose level of Ad/PNP plus fludarabine phosphate (F-araAMP) which demonstrated anti

  • 0 views
  • 21 Mar, 2021
  • 1 location
Donor Stem Cell Transplant With Treosulfan Fludarabine and Total-Body Irradiation for the Treatment of Hematological Malignancies

This phase II trial studies how well a donor stem cell transplant, treosulfan, fludarabine, and total-body irradiation work in treating patients with blood cancers (hematological malignancies

stem cell transplantation
leukemia
cyclosporine
prolymphocytic leukemia
carbon monoxide
  • 0 views
  • 29 May, 2021
  • 1 location
Total Marrow and Lymphoid Irradiation Fludarabine and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

This phase I studies the side effects and best dose of total marrow and lymphoid irradiation when given together with fludarabine and melphalan before donor stem cell transplant in treating

serum bilirubin
stem cell transplantation
leukemia
myeloid leukemia
bone marrow procedure
  • 17 views
  • 19 Feb, 2021
  • 1 location
Intensity Modulated Total Marrow Irradiation Fludarabine Phosphate and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

This phase I trial studies the side effects and the best dose of intensity modulated total marrow irradiation (IMTMI) when given together with fludarabine phosphate and melphalan in treating

bone marrow transplant
cell transplantation
myeloid leukemia
leukemia
stem cell transplantation
  • 13 views
  • 27 Jan, 2021
  • 1 location
Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes

The study is a Phase II clinical trial. Patients will receive intensity modulated total marrow irradiation (TMI) at a dose of 9 Gy with standard myeloablative fludarabine/ i.v. targeted busulfan

fludarabine
myelodysplastic syndromes
blast cells
tacrolimus
busulfan
  • 6 views
  • 11 Jun, 2021
  • 1 location