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Found 274 clinical trials
Tacrolimus and MMF as Post Grafting Immunosuppression After Conditioning With Flu TBI for HLA Matched Family Donor

sibling donor, with fludarabine and low-dose TBI, with pre- and post-transplant immunosuppression with tacrolimus and MMF. B. To evaluate the incidence of grade II-IV GVHD associated with

multiple myeloma
lymphoma
autograft
tacrolimus
hematologic malignancy
  • 42 views
  • 07 Nov, 2020
  • 1 location
CBA Versus FBA Conditioning Followed by Haploidentical Allogeneic HSCT in Treatment of High Risk and Refractory AML

Aim: To evaluated if cladribine based conditioning (CBA) could decrease relapse after haploidentical allogeneic HSCT in high risk and refractory AML patients as compared with fludarabine based

  • 6 views
  • 24 Jan, 2021
  • 1 location
CBA Versus FBA Conditioning Followed by Allogeneic HSCT in Treatment of High Risk and Refractory AML

Aim: To evaluated if cladribine based conditioning (CBA) could decrease relapse after HLA matched HSCT in high risk and refractory AML patients as compared with fludarabine based conditioning

  • 11 views
  • 24 Jan, 2021
  • 1 location
A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC)

) without increasing the chance of not surviving the transplant. Up to 242 patients will be 'randomised' to the trial to receive either the established chemotherapy of fludarabine and melphalan or

remission
myeloablative conditioning
cyclophosphamide
transplant conditioning
total body irradiation
  • 22 views
  • 24 Jan, 2021
  • 22 locations
High-Dose Post-Transplant Cyclophosphamide and Bortezomib (CyBor) for the Prevention of Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

. Patients will receive reduced-intensity or myeloablative conditioning regimen of fludarabine, busulfan, and rabbit anti-thymocyte globulin (rATG). Patients will receive PTCyBor as GvHD prophylaxis.

carbon monoxide diffusing capacity
cell transplantation
myeloablative conditioning
carbon monoxide
fungal infection
  • 1 views
  • 02 May, 2021
  • 1 location
Haploidentical Stem Cell Transplant With Prophylactic Natural Killer DLI for Lymphoma Multiple Myeloma and CLL

This study seeks to examine the investigational use of the conditioning regimen (bendamustine, fludarabine, and rituximab) prior to haploidentical peripheral blood allogeneic stem cell

antiviral
rituximab
diffuse large b-cell lymphoma
cyclophosphamide
transplant conditioning
  • 28 views
  • 26 Jan, 2021
  • 1 location
Allo HSCT Using RIC for Hematological Diseases

This is a phase II trial using a non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related or unrelated donor stem cell infusion. The

burkitt's lymphoma
anemia
myeloproliferative syndromes
hematologic disorder
graft versus host disease
  • 27 views
  • 25 Jan, 2021
  • 1 location
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

malignant diseases. This regimen, consisting of busulfan, fludarabine, and low dose total body irradiation (TBI), is designed to promote engraftment in patients who failed to achieve an acceptable level of

myeloablative conditioning
allogeneic hematopoietic stem cell transplant
total body irradiation
fludarabine
g-csf
  • 17 views
  • 24 Jan, 2021
  • 1 location
Hematopoietic Stem Cell Transplant for Sickle Cell Disease

cell transplants. Doctors will give patients a new drug (fludarabine) to see if this drug changes patients immune system and reduces the patient's cells (host) from rejecting donor cells (graft) after

sirolimus
thalassemia
acute chest syndrome
anti-thymocyte globulin
bone marrow transplant
  • 84 views
  • 28 Jan, 2021
  • 1 location
MiniMUD Study - Unrelated Reduced Intensity Conditioning With Treosulfan for Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies

. The donor is unrelated (identical HLA). The graft is haematological peripheral blood stem cell. The conditioning with reduced intensity is: fludarabine (from day -6 to day -2), treosulfan

carbon monoxide
gleevec
thymoglobulin
fungal infection
myelodysplastic syndromes
  • 13 views
  • 07 Nov, 2020
  • 1 location