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Found 15 clinical trials
Featured trial
ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

ACCL0993: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infection in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

  • 118 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Phase 2, Multicenter, Randomized, Double-blind Study of the Safety, Tolerability, and Efficacy of Intravenous CD101 vs Intravenous Caspofungin Followed by Oral Fluconazole Step-down in the Treatment of Subjects with Candidemia (STRIVE)

A Phase 2, Multicenter, Randomized, Double-blind Study of the Safety, Tolerability, and Efficacy of Intravenous CD101 vs Intravenous Caspofungin Followed by Oral Fluconazole Step-down in the

  • 194 views
  • 25 Mar, 2021
  • 1 location
Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia

dose of liposomal amphotericin (10mg/kg) in addition to standard of care fluconazole therapy. How the enhanced antifungal therapy prevents progression to meningitis in the first 24-weeks and

antifungal therapy
antigen test
HIV Infection
amphotericin
amphotericin b
  • 0 views
  • 23 Dec, 2021
  • 1 location
A Study to Evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole in Subjects With Recurrent Vulvovaginal Candidiasis

The purpose of this study is to evaluate the Efficacy and Safety of SHR8008 capsule In Subjects With Recurrent Vulvovaginal Candidiasis

  • 0 views
  • 22 Oct, 2021
  • 1 location
Glucosamine Sulphate and Ginkgo Biloba as Antifungal Activity for Treating Tinea Pedis

Tinea Pedis infected the feet of about 20-25% of the world population. Tinea Pedis is a fungal infection of the feet and it is easily spread. Oral therapy is usually used for chronic conditions or when topical treatment has failed. The aim of this study is to prove the antifungal …

  • 7 views
  • 23 Jan, 2021
  • 1 location
Fluconazole in Hypercalciuric Patients With Increased 1 25(OH)2D Levels

, fluconazole has been successfully reported to reduce calciuria in patients with CYP24A1 mutation (1 adult) or NPTIIc mutations (1 child), while maintaining a stable renal function. Based on these

  • 0 views
  • 02 Jul, 2021
  • 3 locations
Escalation Antifungal Prophylaxis for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

probable invasive fungal disease (IFD), patients will receive fluconazole during the treatment in the laminar air flow units (LAF). After discharged from LAF units, patients will receive anti-mold

cell transplantation
posaconazole
mold
antifungal agents
invasive fungal infection
  • 2 views
  • 03 Dec, 2021
  • 1 location
PTX3-targeted Antifungal Prophylaxis

This is a prospective genetically-stratified randomized double-blind event-driven multicentre clinical trial to assess the efficacy of posaconazole-based antifungal prophylaxis allocation strategies for patients with acute myeloid leukemia who receive induction chemotherapy. Allocation strategy based on an invasive mold infection genetic risk will be double-blinded.

neutropenia
posaconazole
mold
neutrophils
diflucan
  • 31 views
  • 23 Jan, 2021
  • 5 locations
Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)

Background About half the people who have a hematopoietic stem cell transplant using donor cells get cGVHD. This is chronic graft versus host disease. Immune cells from the donor may see the body tissues in the person as foreign and attack, causing damage. The skin is the most commonly affected …

cancer
extracorporeal photopheresis
neutrophil count
chronic graft versus host disease
ruxolitinib
  • 32 views
  • 19 Jan, 2022
  • 1 location
Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis

To study the clinical effectiveness and safety of amphotericin B with flucytosine-fluconazole therapy for cryptococcal meningitis in patients with HIV infection.

  • 12 views
  • 09 Dec, 2021
  • 2 locations