Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 15 clinical trials
Featured trial
A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

A Randomized, Double-Blinded, Placebo-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB037 in Subjects With Prodromal or Mild Alzheimer's Disease

  • 82 views
  • 25 Mar, 2021
  • 1 location
None
Cardiac Uptake of 18F Florbetapir in Patients Undergoing Chemotherapy

This is a pilot study designed to assess for relative change in cardiac 18F Florbetapir uptake in patients with AL cardiac amyloidosis after appropriate chemotherapy.

nt-probnp
florbetapir
amyloidosis
cardiac mri
  • 0 views
  • 08 Sep, 2021
  • 1 location
None
SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

six-week sleep intervention program. A sub-group of fifty participants will undergo Florbetapir-Positron-emission tomography (PET) imaging during the one-year reassessment to examine the efficacy of

behavior therapy
dementia
cognitive therapy
initial insomnia
cognitive behavioral therapy for insomnia
  • 22 views
  • 27 May, 2021
  • 1 location
None
Cerebral Amyloid Imaging Using Florbetapir (AV-45)

This study is aimed at examining the interest of amyloid radiotracer Florbetapir (18F-AV-45) for the etiological diagnosis of poststroke cognitive impairment and dementia

cognitive impairment
amyloid
stroke
18f-av-45
cognitive assessment
  • 3 views
  • 22 Jan, 2021
  • 1 location
None
Accurate Diagnosis of Multiple Sclerosis Using Hybrid Positron Emission Tomography/Magnetic Resonance (PET/MR)

is a non-invasive molecular imaging technology that can quantitatively monitor physiological or pathological processes in vivo. 18F-labeled thioflavin derivative probe (18F-florbetapir) can bind to

  • 0 views
  • 22 Mar, 2021
  • 1 location
None
Effect of Low Dose Radiotherapy on Brain Amyloidosis in the Treatment of Alzheimer's Disease

dose RT radiotherapy to reduce amyloid deposits in the human brain using molecular imaging (18F-Florbetapir) to show the effectiveness of the treatment on the specific target.

positron emission tomography
amyloid
cognitive assessment
alzheimer's disease
senile plaques
  • 114 views
  • 09 May, 2021
  • 1 location
None
Molecular Imaging of Primary Amyloid Cardiomyopathy

Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis. This project will develop a novel approach to visualize cardiac amyloid deposits using advanced imaging methods. The long-term goal of this work is to identify the mechanisms of cardiac …

immunofixation
cardiac mri
remission
nesiritide
immunohistochemistry
  • 28 views
  • 30 Sep, 2021
  • 1 location
None
MRI and PET Biomarkers for Cognitive Decline in Older Adults

The purpose of this research study is to understand the factors that underlie changes in thinking and memory with increasing age. The investigators will test the usefulness of MRI, PET, and cognitive testing in detecting subtle changes in the brain that precede cognitive decline. An addendum to this study includes …

  • 0 views
  • 29 Apr, 2021
  • 1 location
None
Valacyclovir for Mild Cognitive Impairment

Anti-viral treatment in Mild Cognitive Impairment (MCI) is a Phase II, placebo-controlled, 52-week trial using oral valacyclovir 4 g/day in 50 HSV seropositive, AD biomarker-positive, amnestic mild cognitive impairment (MCI) patients (eMCI and lMCI). The trial will directly address the long-standing viral etiology hypothesis of Alzheimer's disease (AD) which posits …

  • 13 views
  • 18 Mar, 2021
  • 1 location
None
Anti-Viral Clinical Trial for Alzheimer's Disease

Viruses may cause or contribute to the pathology of Alzheimer's disease. This research treatment study at the MEMORY DISORDERS CLINIC is the first ever clinical trial to address this hypothesis. This study includes: brain imaging, clinical assessments, anti-viral research treatment with pills.

mild dementia
cognitive impairment
mini-mental state examination
amyloid
cholinesterase
  • 0 views
  • 13 Oct, 2021
  • 2 locations