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Found 6 clinical trials
Preliminary Investigation of β-hydroxybutyrate Supplementation in Colorectal Cancer Prevention (BHB-CRC)

The aim of this study is to assess the feasibility of beta-hydroxybutyrate (BHB) supplementation in individuals who are undergoing a standard-of-care colonoscopy or flexible sigmoidoscopy.

Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
Examining the Efficacy of Fecal Microbiota Transplantation (FMT) and Dietary Fiber in Patients With Ulcerative Colitis (MINDFUL)

A double-blind, randomized, placebo-controlled clinical trial examining the efficacy and safety of Fecal Microbiota Transplantation (FMT) and high fiber supplementation in patients with active mild to moderate Ulcerative Colitis (UC). All enrolled subjects will provide serological, stool and mucosal specimen at each clinic visit to help further define the alterations …

colitis
fecal microbiota transplantation
flexible sigmoidoscopy
microbiota
ulceration
  • 64 views
  • 23 Mar, 2022
  • 1 location
Characteristics of Immunity in Gut Mucosa Spinal Fluid Lymph Node and Blood of HIV Negative Thais and Thais With HIV Infection

To compare the immunophenotyping and immunochemistry in the gut mucosa of HIV negative and non-acute HIV-infected adults To compare the immunophenotyping of the gut mucosa to that of the peripheral blood in HIV negative and in non-acute HIV-infected subjects To compare the immunophenotyping of the peripheral blood in HIV negative …

HIV Vaccine
  • 20 views
  • 30 Sep, 2021
  • 1 location
Fiber to Reduce Colon Cancer in Alaska Native People

Alaska native people (AN) have the highest recorded incidence and death rate from colon cancer in the world (>90:100,000). We hypothesize that the AN, despite their high consumption of anti-inflammatory and antineoplastic n-3 fish oils, are at increased risk of colon cancer because of colonic butyrate deficiency resulting from their …

colon cancer screening
Accepts healthy volunteers
antineoplastic
cancer screening
screening colonoscopy
  • 7 views
  • 14 Mar, 2022
  • 2 locations
Mitochondrial DAMPs as Mechanistic Biomarkers of Mucosal Inflammation in Crohn's Disease and Ulcerative Colitis (MUSIC)

patients' blood, stools and biopsies that will be correlated to the current gold standard of direct gut visual examination using ileo-colonoscopy and flexible sigmoidoscopy tests (a fibre-optic

ulcerative colitis
colitis
crohn's disease
remission
ulceration
  • 1 views
  • 04 Jun, 2022
  • 1 location
A Systems Biology Approach for Identification of Host and Microbial Mechanisms and Druggable Targets for the Treatment of PSC-IBD (PSC-Vanc)

Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of inflammatory bowel disease (IBD). Although rare, PSC is associated with significant and disproportionate unmet needs; with heightened risks of colorectal cancer and colectomy, and greater all-cause mortality rates compared to matched IBD patients. Unfortunately, no medical therapy has been proven …

colitis
enteropathy
microbiota
antibiotics
primary sclerosing cholangitis
  • 0 views
  • 16 Jun, 2022
  • 1 location