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Found 18 clinical trials
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

This is a first-in survivor, single-arm pilot study with the goal of establishing evidence of feasibility and safety of a combined pharmacologic (metformin) and lifestyle intervention (using an existing digital platform) to prevent diabetes in prediabetic adult survivors of childhood cancer. Primary Objective The primary aim of this proposal is …

insulin
hemoglobin a1c
cancer
insulin resistance
fasting
  • 0 views
  • 14 Oct, 2022
  • 1 location
Impact of Patient's Therapeutic Education in APA and Dietetic on Radiotherapy Reproducibility Sessions for Prostate Cancer (ETADAPT)

The primary objective of this study is to evaluate the impact of Patient's Therapeutic Education (PTE) in Adapted Physical Activity (APA) ans dietetic on the reduction of interventions number on rectal volume (laxative or probe). The secondary objectives are to evaluate the contribution of Patient's Therapeutic Education (PTE) between the …

  • 0 views
  • 23 Apr, 2022
  • 2 locations
Phase II Randomized Trial of Atezolizumab Versus Atezolizumab and Radiation Therapy for Platinum Ineligible/Refractory Metastatic Urothelial Cancer (ART)

This phase II trial compares the effect of adding radiation therapy to an immunotherapy drug called atezolizumab vs. atezolizumab alone in treating patients with urothelial cancer that has spread to other places in the body (metastatic). The addition of radiation to immunotherapy may shrink the cancer, but it could also …

  • 1 views
  • 28 Oct, 2022
  • 38 locations
Effect of STW5 (Iberogast ) and STW5-II (Iberogast N ) on Transit and Tolerance of Intestinal Gas

Study to asess the effects of Iberogast (STW5) and Iberogast N (STW5-II) in intestinal gas transit and abdominal symptoms of patients suffering from irritable bowel syndrome or functional dyspepsia.

bloating
abdominal symptom
  • 12 views
  • 10 Dec, 2021
  • 2 locations
Fecal Microbiota Therapy in Steroid Ineligible Alcoholic Hepatitis

Alcoholic hepatitis, the most florid form of alcoholic liver disease, has a very high short-term mortality of up to 50% and no specific therapies are available other than steroids. Steroids also only show a limited utility in improving the short-term survival and boast no evidence of any long-term benefits. Additionally, …

liver disease
  • 0 views
  • 30 Apr, 2022
  • 1 location
Impacts of Lentils on Metabolism and Inflammation

The overall goal of this investigation is to determine gut microbiome dependent and independent impacts of pulse consumption on metabolic resilience and metabolic risk profiles for type 2 diabetes (T2D) and cardiovascular disease (CVD) risk. Specifically, pulse crop consumption has unrealized potential to fundamentally alter how the body responds to …

fats
diabetes
cardiovascular disease
type 2 diabetes mellitus
fasting
  • 436 views
  • 19 Jun, 2022
  • 1 location
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will …

flecainide
fibrillation
sotalol
antiarrhythmic drug
  • 319 views
  • 08 Jul, 2022
  • 1 location
Biomarkers for Autism and ADHD in Children

Autism (ASD) is one of the frequent neurodevelopmental disorders that children would occur. Many studies have shown that individuals with Autism are more common to experience significant gastrointestinal problems than other individuals. Symptoms include constipation, diarrhea, abdominal pain and gastric reflux. A recent study with 50 children with ASD, 50 …

constipation
deficit
developmental disabilities
microbiota
  • 8 views
  • 06 Aug, 2021
  • 1 location