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Found 53 clinical trials
Advanced Fetal Imaging - Phase II

The goal of Advanced Fetal Imaging - Phase II is to advance fetal MRI imaging by designing MRI coils specifically for pregnant women and testing recently developed MRI image acquisition techniques. The investigators aim to more reliably obtain higher quality fetal MRI images when compared to current clinical fetal MRI.

prenatal
Accepts healthy volunteers
  • 275 views
  • 04 Oct, 2022
  • 1 location
Impact of Von Willebrand Factor-platelet Aggregates in Patients With Type 2B Disease (Von2B)

The working hypothesis is that patients with Von Willebrand Disease-type 2B may have neurological symptoms due to the chronic formation of platelets/Von Willebrand Factor aggregates. Interestingly, several patients present nonspecific neurological symptoms (nystagmus, headaches, memory disorder, …) which may be associated with cerebral microangiopathy and chronic microvessel inflammation secondary to …

  • 5 views
  • 04 Oct, 2022
  • 1 location
Effects of Mepivacaine on the Neurological Sequelae of Cerebral Infarction (MEPI-AVC)

A patient, suffering from cortical blindness after a bi-occipital infarction 1 year earlier, regained near-normal vision in the right visual hemifield a few minutes after subcutaneous administration of mepivacaine. The effect was maintained for several days, and was repeated with each injection of mepivacaine. This clinical improvement is associated with …

  • 0 views
  • 15 Jul, 2022
  • 1 location
Efficacy of Clopidogrel on Incidence of Silent Brain Infarction (ECISBI)

Silent brain infarctions (SBIs) are a manifestation of covert cerebrovascular disease, without obvious clinical deficit, noted very often in patients presenting with a new stroke or new transient ischemic attack. SBIs are linked to a significant increase in risk for subsequent stroke and cognitive decline. However, no biomarker is currently …

  • 0 views
  • 22 Apr, 2022
  • 1 location
Multi-center Randomized Pilot Clinical Trial on Remote Ischemic Conditioning in Acute Ischemic Stroke Within 9 Hours of Onset in Patients Ineligible to Recanalization Therapies (TRICS-9)

Phase II, prospective, randomized, multicenter, open-label, pilot clinical trial comparing remote ischemic conditioning (RIC) plus standard medical therapy to standard medical therapy alone, in patients with acute ischemic stroke within 9 hours of stroke onset that are not eligible to recanalization therapies.

  • 10 views
  • 19 Oct, 2022
  • 3 locations
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

cognitive decline
screening procedures
cancer
cognitive impairment
flutemetamol
  • 178 views
  • 25 Feb, 2022
  • 1 location
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy (SONOBIRDIE)

SONOBIRDIE Trial is a randomized, single-blind, sham-controlled study designed for a demonstration of the safety and effectiveness of sonolysis (continual transcranial Doppler (TCD) monitoring) in reduction of risk of stroke or transient ischemic attack (TIA), brain infarctions and cognitive decline using a 2-MHz diagnostic probe with a maximal diagnostic energy …

endarterectomy
ischemic attack
MRI
stenosis
angiography
  • 6 views
  • 02 May, 2022
  • 1 location
Early Diagnosis of Pseudoprogression Using 11C-Methionine PET-MRI After Concomitant Radiochemotherapy Treatment for Glioblastoma. (TIGRE)

abnormalities (contrast enhancement, FLAIR hypersignal) and can simulate tumor recurrence, even though the corticosteroid improved or kept clinical symptoms stabilized. In view of prognosis, the current

temozolomide
MRI
recurrent tumor
methionine
corticosteroids
  • 14 views
  • 10 Feb, 2022
  • 1 location
Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas (Glio-SIB-Up)

first planning target volume (PTV), including oedema and tumour highlighted on T2 flair magnetic resonance imaging (MRI) sequences, will receive 60.8Gy in 32 daily fractions. The second PTV, including

  • 5 views
  • 27 Apr, 2022
  • 6 locations
BeatPark: Self-rehabilitation in Walking With Parkinson's Disease (BeatPark)

Physical activity has beneficial effects on the quality of walking for persons with Parkinson's disease (PD). However, regular physical activity is still limited in most patients' daily lives. The rhythm of music makes you want to move whether you are sick or not. In addition, it has been found that …

antiparkinsonian agents
hallucinations
  • 0 views
  • 25 Jan, 2022
  • 1 location