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Found 14 clinical trials
MR-US Image Fusion Targeted Biopsy for Single-cell Prostate Cancer Research

The investigators hypothesize that this single-cell analysis can be used to evaluate prostate needle-core biopsies prospectively even in non-homogenous samples by providing profiles of proteomic and phenotypic signatures. These profiles will in turn enable better predictions of the malignant progression of prostate cancers in the settings of current clinical practice.

biopsy of prostate
  • 9 views
  • 27 Jun, 2022
  • 1 location
Genetic, Microenvironmental, and Immunological Factors in Unresectable Pancreatic Ductal Adenocarcinoma

chemotherapeutic agents, making this a lethal disease. The investigators hypothesize that: (i) dissection of genetic, stromal, and immunological factors on endoscopic ultrasound fine needle biopsy (EUS-FNB) tissue

adenocarcinoma
pdac
cancer chemotherapy
breast ductal carcinoma
antineoplastic
  • 0 views
  • 26 Apr, 2022
  • 1 location
Pharmacotyping of Pancreatic Patient-derived Organoids

EUS-FNB samples will be used for organoid cultures, which will be co-cultured with cancer associated fibroblasts derived from the surrounding stroma of the lesion. The organoid cultures will be used for pharmacotyping using relevant chemotherapeutic agents used in the clinic, and the organoid's response compared with the patient's response.

platelet count
antineoplastic
pdac
  • 0 views
  • 22 Mar, 2022
Evaluation of Endoscopic Ultrasound Shear Wave Elastography (EUS-SWE) for the Diagnosis of Pancreatic Adenocarcinoma.

To assess the diagnostic accuracy of Shear Wave elastography (SWE) for the diagnosis of pancreatic adenocarcinoma.

adenocarcinoma
pancreatic adenocarcinoma
endoscopic ultrasound
  • 0 views
  • 07 Oct, 2021
  • 1 location