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Found 1091 clinical trials
Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study (NRG-1-CVDs)

This is an observational study of Neuregulin-1 (NRG-1) plasma levels in patients with different forms of cardiovascular disease including microvascular angina (MVA), heart failure with preserved ejection fraction (HFpEF), as well as, heart failure with reduced ejection fraction (HFrEF) and pulmonary hypertension (PH). Investigators intend to identify cardiovascular diseases which …

neuregulin-1
hypertension
prostaglandin
depression
heart disease
  • 0 views
  • 20 Aug, 2022
  • 1 location
Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation

This is a prospective, case-control study that seeks to learn about the role of genetics in early onset atrial fibrillation (AF) and if genetic testing can be used to improve how the investigators treat atrial fibrillation. The study will enroll 225 participants. Eligible participants will have undergone sequencing for arrhythmia …

Accepts healthy volunteers
fibrillation
arrhythmia
electrocardiogram
cardiomyopathy
  • 0 views
  • 16 Sep, 2022
  • 1 location
Effect of Prior Caesarean Delivery on ICSI Outcome

Although Caesarean section (CS) is often a necessary surgical intervention, it may also be associated with an increased risk of short- and long-term sequelae. It was thought that CS may increase the risk of female subfertility or even infertility. In assisted reproductive technology (ART) cycles, the process of implantation is …

  • 0 views
  • 23 Sep, 2022
  • 1 location
Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study

This study will validate a previously developed pediatric prognostic biomarker algorithm aimed at improving prediction of risk for the later development of chronic graft-versus-host disease (cGvHD) in children and young adults undergoing allogeneic hematopoietic stem cell transplant. By developing an early risk stratification of patients into low-, intermediate-, and high-risk …

bone marrow procedure
antithymocyte globulin
alemtuzumab
transplant conditioning
cyclophosphamide
  • 0 views
  • 14 Jul, 2022
  • 9 locations
Characterizing Asthma Sputum Elasticity in the UCSF Severe Asthma Research Program (CAESAR)

This study is designed to characterize subjects in terms of their sputum phenotype. The purpose of this study is to learn more about the impact of having abnormally elastic sputum on asthma severity by comparing subjects with severe as well as mild/moderate asthma to healthy controls. The characterization will include …

Accepts healthy volunteers
pulmonary function test
methacholine
bronchodilator
methacholine challenge
  • 26 views
  • 23 Mar, 2022
  • 1 location
Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms (AAA-MRE)

The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the …

aortic aneurysm
Accepts healthy volunteers
aaa surgery
  • 8 views
  • 04 May, 2022
  • 1 location
MRI in Randomised Cohorts of Asymptomatic AS

Aortic stenosis is narrowing of the aortic valve, and is the commonest type of valve disease requiring surgery. Current guidelines recommend waiting till patients develop symptoms (chest pain, breathlessness and dizzy spells/fainting) before possible open heart surgery to replace the valve is offered. However, studies using detailed 'MRI' scanning of …

  • 0 views
  • 21 Mar, 2022
  • 1 location
Contribution of Left Atrial Epicardial Fat Quantification by Computed Tomography and Left Atrial Strain by MRI in Atrial-Fibrilation Ablation: "The CTStrain-AF Study" (CTStrain-AF)

Atrial fibrillation ablation (AF) is a standard interventional treatment for patients with symptomatic AF refractory to medical treatment. The known predictive factors for the success of the procedure remain insufficient to predict the probabilities of success and to appropriately select the patients who could benefit the most from this procedure. …

  • 0 views
  • 15 Sep, 2022
Arrhythmias in Pulmonary Hypertension Assessed by Continuous Long-term Cardiac Monitoring (ASPIRE)

Arrhythmias are considered a prominent phenomenon in pulmonary hypertension (PH) as the disease progresses. According primarily to retrospective studies with up to 24 hours of monitoring, supraventricular tachycardias (SVT) can be found in 8-35% of patients, with significant impact on survival. Furthermore, a few prospective studies to date deploying short-term …

right heart catheterization
heart disease
hypertension
pulmonary arterial hypertension
cardiac monitoring
  • 0 views
  • 17 May, 2022
  • 1 location
Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.

  • 0 views
  • 20 Oct, 2021
  • 1 location